Abstract
The secretory immune system of the eye is designed to protect the ocular surface against microbial challenge and infectious disease.1 This immunological role is mediated primarily through secretory IgA (sIgA) antibodies, which are produced by plasma cells in interstitial areas of the lacrimal gland and are selectively transported to tears by secretory component (SC), the polymeric TgA receptor.1 After delivery to the eye’s anterior surface, sIgA antibodies may act to prevent viral internalization, inhibit bacterial colonization, curtail parasitic infestation and attenuate toxin-related damage.2
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© 1994 Springer Science+Business Media New York
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Wickham, L.A., Huang, Z., Lambert, R.W., Sullivan, D.A. (1994). Sialodacryoadenitis Virus Infection of Rat Lacrimal Gland Acinar Cells. In: Sullivan, D.A. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes. Advances in Experimental Medicine and Biology, vol 350. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2417-5_34
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DOI: https://doi.org/10.1007/978-1-4615-2417-5_34
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