Skip to main content
SpringerLink
Log in

Aspects of Lyme Carditis

  • Chapter
Book cover Lyme Borreliosis

Part of the book series: NATO ASI Series ((NSSA,volume 260))

  • 95 Accesses

Abstract

The cardiac manifestations of Lyme borreliosis (Lyme carditis) were first characterized by Steere et al1 in 1980. In this article, atrioventricular block, perimyo-carditis and mild heart failure were described as the features of Lyme carditis. The first specific articles on Lyme carditis in Europe were published in 19842,3, although already in 1973 a French patient was described with typical features of Lyme carditis (erythema migrans, arthralgias, Wenckebach atrioventricular (AV) block and perimyocarditis), but the diagnosis could only be confirmed retrospectively in 1985, when the immunofluorescence assay became available for B. burgdorferi and the preserved serum was found positive in this patient4. Other authors, however, had previously related cardiac complaints and abnormalities to other manifestations of Lyme borreliosis5,6. In recent years, the number of publications on Lyme carditis has increased rapidly, extending the pattern of Lyme carditis with other cardiac manifestations and showing the diversity of the possible expressions of this disease7–13.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Steere AC, Batsford WP, Weinberg M, Alexander J, Berger HJ, Wolfson S, Malawista SE. Lyme carditis: cardiac abnormalities of Lyme disease. Ann Intern Med 1980; 93 (1): 8–16.

    Article  PubMed  CAS  Google Scholar 

  2. Cornuau C, Bernard M, Daumas PL, Oblet B, Poirot G, Valois M. Les manifestations cardiaques de la maladie de Lyme. A propos de deux observations. (Cardiac manifestations of Lyme disease. Apropos of 2 cases). Ann Cardiol Angeiol (Paris) 1984; 33 (6): 395–399.

    CAS  Google Scholar 

  3. Houwerzijl J, Root JJ, Hoogkamp-Korstanje JAA. A case of Lyme disease with cardiac involvement in the Netherlands (letter). Infection 1984; 12: 358.

    Article  Google Scholar 

  4. Schott B. Erytheme de Lipschtz avec Atteinte Cardiaque. A Propos d’une Cas: Etiology Méconne de BAV Paroxystique. Synthèse et Rapport avec la Maladie de Lyme aux USA. Thesis, Louis Pasteur University, Strasbourg, France, 1985.

    Google Scholar 

  5. Bannwarth A. Chronische lymphocytaere Meningitis, entzuentliche Polyneuritis und Rheumatismus. Arch Psychiatr Nervenkr 1941; 113: 284–376.

    Article  Google Scholar 

  6. Hopf HC. Acrodermatitis Chronica Atrophicans (Herxheimer) und Nervensystem, in: “Monographien aus dem Gesamtgebiete der Neurologie und Psychiatrie”, vol 114., Berlin-Heidelberg-New York: Springer, 1966; 70–71.

    Google Scholar 

  7. Linde van der MR, Crijns HJGM, de Koning J, Hoogkamp-Korstanje JAA, de Graaf JJ, Piers DA, van der Galien A, Lie KI. Range of atrioventricular conduction disturbances in Lyme borreliosis: a report of 4 cases and review of other published reports. Br Heart J 1990; 63: 162–168.

    Article  PubMed  Google Scholar 

  8. Stanek G, Klein J, Bittner R, Glogar D. Isolation of Borrelia burgdorferi from the myocardium of a patient with longstanding cardiomyopathy. N Engl J Med 1990; 322: 249–252.

    Article  PubMed  CAS  Google Scholar 

  9. Linde van der MR. Lyme carditis: clinical characteristics of 105 cases. Scand J Infect Dis (suppl) 1991; 77: 81–84.

    Google Scholar 

  10. Vlay SC, Dervan JP, Elias J, Kane PP, Dattwyler R. Ventricular tachycardia associated with Lyme carditis. Am J Med 1991; 121: 1558–1560.

    CAS  Google Scholar 

  11. Jukema JW, Werner HA, Reinders Folmer SCC, Wesdorp JCL. Lyme-borreliose en gedilateerde cardiomyopathie. Ned Tijdschr Cardiol 1992; 6: 16–19.

    Google Scholar 

  12. Linde van der MR, Ballmer PE. Lyme carditis. In: Weber K, Burgdorfer W, ed. Aspects of Lyme Borreliosis. Berlin-Heidelberg: Springer Verlag, 1993; 131–151.

    Chapter  Google Scholar 

  13. Wunderlich E, Graf A, Thess G, Foelske H. Dilatative Herzmukelerkrankung als Folge einer chronischen Lyme-Karditis. Z Kardiol 1990; 79: 599–600.

    CAS  Google Scholar 

  14. Steere AC, Malawista S, Hardin J, et al. Erythema chronicum migrans and Lyme arthritis: The enlarging clinical spectrum. Ann Intern Med 1977; 86: 685–698.

    Article  PubMed  CAS  Google Scholar 

  15. Rubin DA, Sorbera C, Nikitin P, McAllister A, Wormser GP, Nadelman RB. Prospective evaluation of heart block complicating early Lyme disease. Pace 1992; 15: 252–255.

    Article  PubMed  CAS  Google Scholar 

  16. Schmidt R, Kabatzki J, Hartung S, Ackermann R. Erythema-migrans-Borreliose in der Bundesrepu blik Deutschland: Epidemiologie und klinisches Bild. Dtsch Med Wochenschr 1985; 110: 1803–1807.

    Article  PubMed  CAS  Google Scholar 

  17. Dournon E, Assous M, Fourcade C. Clinical features of Lyme disease in France. In: Abstract Book of the 27th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), 4–7 Oct 1987, New York, USA, 1987; 319: 1274.

    Google Scholar 

  18. Kaell AT, Volkman DJ, Gorevic PD, Dattwyler RJ. Positive Lyme serology in subacute bacterial endocarditis: a study of four patients. JAMA 1990; 264: 2916–2918.

    Article  PubMed  CAS  Google Scholar 

  19. Cox J, Krajden M. Cardiovascular manifestations of Lyme disease. Am Heart J 1991; 122: 1449–1455.

    Article  PubMed  CAS  Google Scholar 

  20. Cary NRB, Fox B, Wright DJM, Cutler SJ, Shapiro LM, Grace AA. Fatal Lyme carditis and endodermal heterotopia of the atrioventricular node. Postgrad Med J 1990; 66: 134–136.

    Article  PubMed  CAS  Google Scholar 

  21. Artigao R, Torres G, Guerrero A, Jimenez-Mena M, Bayas Paredes M. Am J Med 1991; 90: 531–533.

    PubMed  CAS  Google Scholar 

  22. Bianchi G, Rovetta, Monteforte P, Fumarola D, Trevisan G, Crovato F, Cimmino MA. Articular involvement in European patients with Lyme disease. A report of 32 Italian patients. Br J Rheum 1990; 29: 178–180.

    Article  CAS  Google Scholar 

  23. Slavik Z, Janousek J, Tax P, Chaloupecky V. Cardiac involvement in Lyme disease. Case report. Cs Pediat 1990; 45: 276–278.

    CAS  Google Scholar 

  24. Patial RK, Kashyap S, Bansal SK, Sood A. Lyme disease in a Shimla boy. JAPI 1990; 38: 503–504.

    PubMed  CAS  Google Scholar 

  25. Carlberg H, Naito S. Lyme Borreliosis. A review and present situation in Japan. J Derm 1991; 18: 125–142.

    CAS  Google Scholar 

  26. Stewart A, Glass J, Patel A, Watt G, Cripps A, Clancy R. Lyme arthritis in the Hunter Valley. Med J Aust 1982; 1: 139.

    PubMed  CAS  Google Scholar 

  27. Woolf PK, Lorsung EM, Edwards KS, Li KI, Kanengiser SJ, Ruddy RM, Gewitz MH. Electrocardio graphic findings in children with Lyme disease. Pediatr Emerg Care 1990; 7: 334–336.

    Article  Google Scholar 

  28. Kapusta P, Fauchier JP, Cosnau P, Huguet R, Grezard O, Rouesnel P. Troubles conductifs sino-auriculaires et auriculo-ventriculaires de la maladie de Lyme. A propos de deux observations. (Sinoatrial and atrioventricular-conduction disorders in Lyme disease. Apropos of 2 case reports). Arch Mal Coeur 1986; 79 (9): 1361–1366.

    PubMed  CAS  Google Scholar 

  29. Lavaud P, Etienne J, Chamot E et al. Bloc auriculo- ventriculaire aiqu associé une maladie de Lyme. Un cas confirmé par sérologie. (Acute auriculo-ventricular block associated with Lyme disease. A case confirmed by serology (letter)). Presse Med 1985; 14 (39): 2020.

    Google Scholar 

  30. Allai J, Coisne D, Thomas P et al. Manifestations cardiaques de la maladie de Lyme. (Cardiac manifestations of Lyme disease). Ann Med Interne 1986; 137 (5): 372–374.

    Google Scholar 

  31. Lorcerie B, Boutron MC, Portier H, Beuriat P, Ravisy J, Martin F. Manifestations pericardiques de la maladie de Lyme (Pericardial manifestations of Lyme disease). Ann Med Interne (Paris) 1987; 138: 601–603.

    CAS  Google Scholar 

  32. Veyssier P, Davous N, Kalousstian E, Maitre B, Lallement PY, Serret A. Atteintes cardiaques au cours de la maladie de Lyme. Deux observations. (Cardiac involvement in Lyme disease. 2 case-s). Rev Med Interne 1987; 8: 357–360.

    Article  PubMed  CAS  Google Scholar 

  33. O’Connell JB, Henkin RE, Robinson JA, Subramanian R, Path MRC, Scanlon PJ, Gunnar RM. Gallium-67 imaging in patients with dilated cardiomyopathy and biopsy-proven myocarditis. Circulation 1984; 70: 58–62.

    Article  PubMed  Google Scholar 

  34. Jacobs JC, Rosen JM, Szer IS. Lyme myocarditis diagnosed by gallium scan. J Pediatr 1984; 105: 950–952.

    Article  PubMed  CAS  Google Scholar 

  35. Rienzo RJ, Morel DE, Prager D, Barron L, Post R. Gallium avid Lyme myocarditis. Clin Nucl Med 1987; 12: 475–476.

    Article  PubMed  CAS  Google Scholar 

  36. Ponsonnaille J, Citron B, Karsenty B et al. Myocardite aique au cours d’un syndrome de Lyme. Interet de la scintigraphic myocardique au gallium 67. (Acute myocarditis in Lyme’s syndrome. Value of myocardial scintigraphy with gallium 67). Arch Mal Coeur 1986; 79: 1946–1950.

    PubMed  CAS  Google Scholar 

  37. Linde van der MR, Crijns HJGM, Lie KI. Transient complete atrioventricular block in Lyme disease. Chest 1989; 96: 219–221.

    Article  PubMed  Google Scholar 

  38. Duray PH, Steere AC. The spectrum of organ and systems pathology in human Lyme disease. Zentralbl Bakteriol Hyg (A) 1986; 263: 169–178.

    CAS  Google Scholar 

  39. Koning de J, Bosma RB, Hoogkamp-Korstanje JAA. Demonstration of spirochaetes in patients with Lyme disease with a modified silver stain. J Med Microbiol 1987; 23: 261–267.

    Article  PubMed  Google Scholar 

  40. Koning de J, Hoogkamp-Korstanje JAA, Linde van der MR et al. Demonstration of spirochetes in cardiac biopsies of patients with Lyme disease. J Inf Dis 1989; 160: 150–153.

    Article  Google Scholar 

  41. Dunica S, Piette JC, Nassar N, Beaufils P. Une nouvelle cause de bloc auriculo-ventriculaire aiou transitoire: la maladie de Lyme. (A new cause of acute transitory auriculoventricuiar block: Lyme disease). Arch Mal Coeur 1986; 79: 1251–1255.

    PubMed  CAS  Google Scholar 

  42. Fauchier JP, Cosnay P, Sirinelli A, Moquet B, Rabut H. Myocardite de Lyme sans troubles conductifs auriculo-ventriculaires. Press Med 1988; 17 (38): 2036–2037.

    CAS  Google Scholar 

  43. Mayer-Weber W, van der Linde MR, Hassler D. Therapy of Lyme Carditis. In: Weber K, Burgdorfer W, ed. Aspects of Lyme borreliosis. Berlin-Heidelberg: Springer Verlag, 1993; 344–349.

    Chapter  Google Scholar 

  44. Dattwyler RJ, Halperin JJ, Pass H, Luft BJ. Ceftriaxone as effective therapy in refractory Lyme disease. J Infect Dis 1987; 1322–1325.

    Google Scholar 

  45. Dattwyler RJ, Halperin JJ, Volkmann DJ, Luft BJ. Treatment of late Lyme borreliosis — randomized comparison of ceftriaxone and penicillin. Lancet 1988; ii: 1191–1194.

    Google Scholar 

  46. Marcus LC, Steere AC, Duray PH, Anderson AE, Mahoney EB. Fatal pancarditis in a patient with coexistent Lyme disease and babesiosis: demonstation of spirochetes in the myocardium. Ann Intern Med 1985; 103: 374–376.

    Article  PubMed  CAS  Google Scholar 

  47. Koning de J, Houwerzijl J. Personnal communication.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Cardiology, Nij Smellinghe Hospital, 9202 NN, Drachten, The Netherlands

    Marcel R. van der Linde

  2. Department of Cardiology, Thoraxcenter University Hospital of Groningen, 9713 EZ, Groningen, The Netherlands

    Harry J. G. M. Crijns

Authors
  1. Marcel R. van der Linde
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Harry J. G. M. Crijns
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. St. George’s Hospital Medical School, University of London, London, UK

    John S. Axford  & David H. E. Rees  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer Science+Business Media New York

About this chapter

Cite this chapter

van der Linde, M.R., Crijns, H.J.G.M. (1994). Aspects of Lyme Carditis. In: Axford, J.S., Rees, D.H.E. (eds) Lyme Borreliosis. NATO ASI Series, vol 260. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2415-1_7

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-2415-1_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6024-7

  • Online ISBN: 978-1-4615-2415-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation