Pitfalls in the Laboratory Diagnosis of Lyme Borreliosis
Over a decade has passed since the identification of Borrelia burgdorferi as the causative agent of Lyme borreliosis, yet laboratory diagnosis of Lyme borreliosis remains problematic. Conventional bacteriological methods of microscopy and culture have been used with only limited success. Numbers of spirochaetes are too low for diagnosis by direct microscopic examination and pseudospirochaetes may falsely be reported as positive. Results of culture for Borrelia in the United Kingdom have been disappointing, with only one isolate obtained to date in our laboratory.
KeywordsDermatol Sera Plague
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