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The Alu-Domain of the Signal Recognition Particle

  • Katharina Strub
  • Nicole Wolff
  • Suzanne Oertle

Abstract

A fundamentally important task of all eucaryotic cells is to direct proteins to their final intra-or extracellular location. A cytoplasmic component, the signal recognition particle (SRP), plays a key role in one of these sorting processes. It recognizes secretory, lysosomal and membrane proteins and efficiently targets them to the endoplasmic reticulum (ER). The ER is the first and common subcellular compartment in the localization pathway of these proteins. SRP consists of 6 polypeptides and 1 RNA molecule (Walter and Blobel, 1982) and belongs therefore to a group of cellular components that are called ribonucleoproteins.

Keywords

Signal Recognition Particle Micrococcal Nuclease Secondary Structure Model Nascent Chain Nascent Polypeptide Chain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Katharina Strub
    • 1
  • Nicole Wolff
    • 1
  • Suzanne Oertle
    • 2
  1. 1.Département de Biologie CellulaireUniversité de Genève Sciences III 30Genève 4Switzerland
  2. 2.Hirnforschungs-Institut der Universität ZürichZürichSwitzerland

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