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The environmental implications of genetic engineering in the food industry

  • S. Roller
  • D. Praaning-Van Dalen
  • P. Andreoli

Abstract

Since the end of World War 2, insect and pest control in agriculture has been heavily dependent on the use of chemical insecticides and pesticides. However, several of these synthetic compounds accumulated in the environment, in the food chain and sometimes in human adipose tissue and had acute or chronic side-effects in non-target organisms. Furthermore, due to the intensive use of pesticides, resistance developed in some pest populations. Consequently, and as a result of the high cost of biotechnological development, the first wave of research in food-related biotechnology was instigated and supported by the large seed and agro- chemical industries. This has resulted in a preponderance of novel plant, animal and microbial strains genetically engineered for the benefit of the farmer or fertiliser/pesticide producer. For example, transgenic plants carrying the traits of pest and disease resistance have already been developed. The products of this technology, one of the first and most successful practical applications of the new biotechnology, are already on the market.

Keywords

Transgenic Tomato Recombinant Yeast Environmental Implication Antisense Technology Transgenic Oilseed Rape 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Addy, N.D. (1991) Impact of biotechnology on vegetable processing, in Biotechnology and Food Ingredients, eds. I. Godberg and R. Williams. Van Nostrand Reinhold, New York, pp. 307-316.Google Scholar
  2. Anon (1977) Federation of American Societies for Experimental Biology, National Technical Information Service PB-274 668.Google Scholar
  3. Anon (1990) Biotechnol. Bull.May.Google Scholar
  4. Anon (199Oa) Antisense genes for long-life fruit. AFRC Annual Report, 1989-90, AFRC, Swindon, pp. 14-15.Google Scholar
  5. Anon (1990b) Food Proc. April.Google Scholar
  6. Anon (1991) Biotechnol Newswatch 11 (6), 6.Google Scholar
  7. Anon (1991a) ICI Corp. Abstracts in Biocommerce 13 (14), 8.Google Scholar
  8. Anon (1992) DNA plant technology gets patent for antifreeze proteins. Food Technol August, 72.Google Scholar
  9. Anon (1993) Data on genetically engineered tomato submitted to FDA. Food Technol May, 36.Google Scholar
  10. Anon (1993a) Dispute over GMO registers could land government in hot water. Biotechnol Bull March, 2.Google Scholar
  11. Anon (1993b) Transgenic potatoes. Agro-Food Industry Hi-Tech March/April 44.Google Scholar
  12. Anon(1993c)FDA Considers labelling of bio-engineered foods. Biotechnol Bull June 3.Google Scholar
  13. Anon (1993d) Calgene files suit against Enzo Biochem. Biotechnol Bull February 6–7.Google Scholar
  14. Anon (1993e) Calgene receives brassica transformation patent. Biotechnol Bull March 6.Google Scholar
  15. Anon (1993f) Rennet substitute affirmed as GRAS. Food Technol July, 72.Google Scholar
  16. Bains, W. (1990) Antisense technology can have substantial impact in several novel aDolica- tion areas. Genet. Eng News Nov./Dec., 4.Google Scholar
  17. Balbás, P Soberon, X., Zurita, M., Comeli, H., Valle, F., Flores, N. and Bolivar, F (1986)Plasmid vector pBR322 and its special-purpose derivatives - a review Gene 50 3–40.CrossRefGoogle Scholar
  18. Baltimore D. (1970) RNA-dependent DNA polymerase in virions of RNA tumour viruses Nature 1209, 11.Google Scholar
  19. Barbano, D.M. and Rasmussen, R.R. (1991) Cheese yield performance of fermentation-produced chymosin and other milk coagulants. J. Dairy Sci 75 1–12.CrossRefGoogle Scholar
  20. Bleecker, A.B. (1989) Prospects for the use of genetic engineering in the manipulation of ethylene biosynthesis and action in higher plants, in Biotechnology and Food Quality eds b.-D. Kung, D.D. Bills and R. Quatrano. Butterworths, Boston pp 159–165.Google Scholar
  21. Bleecker A.B. Kenyon, W.H., Somerville, S.C. and Kende, H. (1986) Use of monoclonal antibodies in the purification and characterisation of ACC synthase, an enzyme in ethylene biosynthesis. Proc. Natl Acad. Sci. 83, 7755–7759.CrossRefGoogle Scholar
  22. Bridges, I.G., Schuch, W.W. and Grierson, D. (Assignee: ICI) (1988) Tomatoes with reduced fruit-ripening enzymes. European Patent Application 0 341 885.Google Scholar
  23. Bryant, J.A. (1989)Antisense RNA makes good sense. TIBTECH 7 (2), 20.CrossRefGoogle Scholar
  24. Celenza, J.A. and Carlson, M. (1985) Rearrangement of the genetic map of chromosome VII of Saccharomyces cervisiae. Genetics 109, 661–664.Google Scholar
  25. Crawley, M.J., Hails, R.S., Rees, M., Kohn, D. and Buxton, J. (1993) Ecology of transgenic oilseed rape in natural habitats. Nature 363, 620–623.CrossRefGoogle Scholar
  26. Do Carmo-Sousa, L. (1969) Distribution of yeast in nature, in The Yeast, eds. A.H. Rose and J.S. Harrison. Academic Press, London, pp. 79–106.Google Scholar
  27. Duxbury, D.D. (1993) Genetic researchers boost plant starch yields. Food Proc. February, 66..Google Scholar
  28. EC (1990) Council Directive on the contained use of genetically modified microorganisms, 90/219/EEC. Off. J. Eur. Commun. L117, 1–14.Google Scholar
  29. EC (1990) Council Directive on the deliberate release into the environment of genetically modified organisms, 90/220/EEC. Off. J. Eur. Commun. L117, 15–27.Google Scholar
  30. Elkington,J.(1993) Campbell in the soup? Biotechnol. Bull. 12 (1), 1.Google Scholar
  31. Federation of American Societies for Experimental Biology (1977) National Technical Information Service PB-274 668.Google Scholar
  32. Fink, G. R. et al. (1978) Yeast as a host for hybrid DNA, in Genetic Engineering, 2, eds. H. W. Boyer and S. Nicosia. Elsevier/North-Holland, Amsterdam, pp. 163–171.Google Scholar
  33. FDA (1984) Lactase from Kluyveromyces lactis, GRAS affirmed, 21 Code of Federal Regulations (CFR) 184.1388. 49, Federal Register 47387, December 4.Google Scholar
  34. FDA (1992) Chymosin from Kluyveromyces lactis, GRAS affirmed, 21 Code of Federal Regulations (CFR) 184.1685 57, Federal Register 6476–6479, February 25.Google Scholar
  35. Fox, J.L. (1993a) FDA advisory panel moves Monsanto's BST. BioTechnology 11, 554–555.Google Scholar
  36. Fox, J.L. (1993b) FDA panel ponders labels for BST-derived foods. BioTechnology 11, 656–657.Google Scholar
  37. Fox, J.L. (1993c) FDA reexamines biotech policy. BioTechnology 11, 656.Google Scholar
  38. Fraley, R. (1992) Sustaining the food supply. BioTechnology 10, 40–43.CrossRefGoogle Scholar
  39. Frommer, Wet al. (1989) Safe biotechnology. III. Safety precautions for handling microorganisms of different risk classes. Appl. Microb. Biotechnol. 30, 541–552.Google Scholar
  40. Gatignol, A., Dassain, M. and Tiraby, G. (1990) Cloning of S. cerevisiae promoters using a probe vector based on phleomycin resistance. Gene 91, 35–41.CrossRefGoogle Scholar
  41. Giovannoni, J.J., DellaPenna, D., Bennett, A.B. and Fischer, R.L. (1989) Expression of a chimeric polygalacturonase gene in transgenic rin (ripening inhibitor) tomato fruit results in polyuronide degradation but not fruit softening. Plant Cell 1, 53.Google Scholar
  42. Goodman, R.M., Hauptli, H., Crossway, A. and Knauf, V.C. (1987) Gene transfer in crop improvement. Science 236, 48.CrossRefGoogle Scholar
  43. Gorner, P. and Kotulak, R. (1991) Gene splicers putting new food on the table. Food Technol. August, 46–103.Google Scholar
  44. Gottlin-Ninga, G. and Kaback, C.B. (1986) Isolation and functional analysis of sporulation- induced transcribed sequences from Saccharomyces cerevisiae. Mol. Cell Biol. 6, 2185.Google Scholar
  45. Gross, K.C. (1990) Recent developments in tomato fruit softening. Postharvest News Inf. 1 (2), 109–112.Google Scholar
  46. Harlander, S.K. (1987) Biotechnology: Emerging and expanding opportunities for the food industry. Nutr. Today 22 (4), 21–29.CrossRefGoogle Scholar
  47. Harlander, S.K. (1993) Food biotechnology: toward the twenty first century, in Recent Advances in US Food Technology, Proc. 1FT Conf., Wallingford, UK, 1992Google Scholar
  48. Hobson, G. (1993) The transgenic tomato, the story so far. Grower January, 14.Google Scholar
  49. Kappe, R. and Muller, J. (1978) Cultural and serological follow-up of two oral administrations of baker's yeast to a human volunteer. Mykosen 30, 357–368.CrossRefGoogle Scholar
  50. Kareiva, P. (1993) Transgenic plants on trial. Nature 363, 580.CrossRefGoogle Scholar
  51. Kidd, G. (1993) DNAP takes the lead in genetic subtraction. BioTechnology 11, 874.CrossRefGoogle Scholar
  52. Kok, E.J., Reynaerts, A. and Kuiper, H.A. (1993) Novel food products from genetically modified plants: do they need additional food safety regulations? Trends Food Sci. Technol. 4, 42–48.CrossRefGoogle Scholar
  53. M., Sanders, R.A., Bolkan, H., Waters, C., Sheehy, R.E. and Hiatt, W.R. (1992).Postharvest evaluation of transgenic tomatoes with reduced levels of polygalacturonase: processing, firmness and disease resistance. Postharvest Biol. Technol. 1 241–255 CrossRefGoogle Scholar
  54. Lex, M. (1993) Letter from Brussels. BioBulletin 14 (1), 10.Google Scholar
  55. Maxam, A.M. and Gilbert, W. (1977) A new method for sequencing DNA. Proc. Natl Acad Sci. USA 74, 560–565.CrossRefGoogle Scholar
  56. Maat, J. and Smith, A.J.H. (1978) A method for sequencing restriction fragments with dideoxynucleoside triphosphates. Nucleic Acids Res. 5, 4537–4546.CrossRefGoogle Scholar
  57. Maat, J., Verrips, C.T., Ledeboer, A.M. and Edens, L. (1983) DNA molecules comprising the genes for preprochymosin and its maturation forms and microorganisms transformed thereby. European Patent Application 077109.Google Scholar
  58. Miflin, B.J. (1993) Bringing plant biotechnology to the market - the next steps Agro-Food Ind. Hi-Tech January/February, 3–5.Google Scholar
  59. Miller, P. D. and Morrison, R. A. (1991) Biotechnological applications in the development of new fruits and vegetables, in Biotechnology and Food Ingredients, eds. I. Godberg and R. Williams. Van Nostrand Reinhold, New York, pp. 13–29.Google Scholar
  60. Needleman, R.B., Kaback, D.B., Dubin, R.A., Perkins, E.L., Rosenburg, N.G., Sutherland, K.A., Forrest, D.B. and Michels, C.A. (1984) Mai 6 of Saccharomyces cerevisiae: a complex genetic locus containing three genes required for maltose fermentation Proc Natl. Acad. Sci. USA 81, 2811.CrossRefGoogle Scholar
  61. OECD (1986) Recombinant DNA Safety Considerations, OECD, 2, rue André-Pascal, 75775 Paris Cedex 16, France.Google Scholar
  62. Osinga, K.A. (1992) Genetische Verbesserung vom Backerhefestammen. Getreide, Mehl Brot 3,73-75.Google Scholar
  63. Praaning-van Dalen, D.P. (1992) Application and regulatory position of Maxiren. Bull Int Dairy Fed. (IDF) 269, 8–12.Google Scholar
  64. Redenbaugh, K., Hiatt, W., Martineau, B., Kramer, M., Sheeay, R., Sanders, R. Houck, C. and Emlay, D. (1992) Safety Assessment of Genetically Engineered Fruit and Vegetables: A Case Study of the Flavr Savr Tomato. CRC Press, Boca Raton, FL.Google Scholar
  65. Rothstein, R.J. (1983) One-step gene disruption in yeast. Methods Enzymol. 101 202.CrossRefGoogle Scholar
  66. Sambrook, J., Maniatis, T. and Fritsch, E.F. (1989) Molecular Cloning: A Laboratory Manual, 2nd edition. CSHLP, Cold Spring Harbor, NY.Google Scholar
  67. Scher, M. (1993a) Biotechnology's evolution spurs food revolution. Food Proc January 36–43.Google Scholar
  68. Scher,M.(1993b) The human factor. Food Process. April, 117.Google Scholar
  69. Sharp, W.R., Evans, D.A. and Ammirato, P.V. (1984) Plant genetic engineering: Designing crops to meet food industry specifications. Food Technol. February, 112.Google Scholar
  70. Sheehy, R.E., Kramer, M. and Hiatt, W.R. (1988) Reduction of polygalacturonase activity m tomato fruit by antisense RNA. Proc. Natl. Acad. Sci. USA 85, 8805.CrossRefGoogle Scholar
  71. Simon-Moffat, A. (1993) ICI demerger signals new direction in biotech world. Genet Ens News 13 (10) 1, 36.Google Scholar
  72. Smith, C.J.S., Watson, C.F., Ray, J., Bird, C.R., Morris, P.C., Schuch, W. and Grierson, D. (1988) Antisense RNA inhibition of polygalacturonase gene expression in transgenic tomatoes. Nature 334, 724.CrossRefGoogle Scholar
  73. US Federal Register, Part X. Department of Agriculture, 7 CFR Part 340, Final Rule March 31 1993.Google Scholar
  74. Van den Berg, J.A., van der Laken, K.J., van Ooyen, A.J.J., Renniers, T.C.H.M., Rietveld K., Schaap, A., Brake, A.J., Bishop, R.J., Schultz, K., Moyer, D., Richmann, M. and Shuster, J.R. (1990) Kluyveromyces as a host for heterologous gene expression: expression and secretion of prochymosin. BioTechnology 8, 135–139.CrossRefGoogle Scholar
  75. Van der Wilden, W. (1990) Recent developments in yeast technology, in Proc. 71st Coni. British Soc. Baking, pp. 20–26.Google Scholar
  76. Van Leen, R.W., Bakhuis, J.G., van Beckhoven, F.W.C., Burger, H., Dorssers, L.C.J., Hommes, R.W.J., Lemson, P.J., Noordam, B., Persoon, N.L.M. and Wagemaker, G. (1991) Production of human interleukin-3 using industrial microorganisms. BioTechnology 9,47–52.CrossRefGoogle Scholar
  77. Van Wagner, L.R. (1993) Foreseeing the death of Delaney. Food Proc. February, 31–32.Google Scholar
  78. Ward, M. (1993) European Commission proposes ban on BST. BioTechnology 11', 869.CrossRefGoogle Scholar
  79. Wasserman, B.P. (1990) Expectations and role of biotechnology in improving fruit and vegetable quality. Food Technol. 44 (2), 68.Google Scholar
  80. Whitaker, R.J. and Evans, D.A. (1987) Plant biotechnology and the production of flavour compounds. Food Tech nol. September, 86.Google Scholar
  81. Whitaker, R.J. and Evans, D.A. (1990) Biotechnology and the production of food ingredients, in Biotechnology and Food Safety, eds. D.D. Bills and S.-D. Kung. ButterworthHeinemann, Boston, pp. 291–310.Google Scholar
  82. WHO (1972) 15th Report of the Expert Committee, FAO Nutrition Meetings Report Series 50. WHO Technical Report Series 488.Google Scholar

Copyright information

© Springer Science+Business Media Dordrecht 1994

Authors and Affiliations

  • S. Roller
  • D. Praaning-Van Dalen
  • P. Andreoli

There are no affiliations available

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