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Photodynamic therapy for cancer of the head and neck

  • Chapter
Head and Neck Cancer

Part of the book series: Cancer Treatment and Research ((CTAR,volume 74))

Abstract

Photodynamic therapy (PDT) is a therapeutic modality that utilizes a photosensitizing drug that selectively localizes in tumors and, on activation by exposure to light, results in preferential tumor necrosis. Like all new therapies directed to cancer, this modality was initially greeted with great enthusiasm and was heralded as an excellent therapy, not only for early superficial cancer but also the more advanced tumors. Time and experience have tempered this unrealistic expectation and, therefore, in spite of its initial promise, PDT remains for the present an investigational modality whose potential has yet to be realized. Much basic research and more clinical trials are required before its exact role in contemporary cancer therapy can be accurately defined, but one remains optimistic that this will soon occur. Two components are necessary for this therapy to be utilized, that is, a photosensitizer drug and a laser to activate the drug.

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Authors
  1. Jack L. Gluckman
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  2. Louis G. Portugal
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Editor information

Editors and Affiliations

  1. M. D. Anderson Cancer Center, The University of Texas, Houston, Texas, USA

    Waun Ki Hong M.D.  & Randal S. Weber M.D.  & 

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© 1995 Springer Science+Business Media New York

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Gluckman, J.L., Portugal, L.G. (1995). Photodynamic therapy for cancer of the head and neck. In: Hong, W.K., Weber, R.S. (eds) Head and Neck Cancer. Cancer Treatment and Research, vol 74. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2023-8_9

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  • DOI: https://doi.org/10.1007/978-1-4615-2023-8_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5837-4

  • Online ISBN: 978-1-4615-2023-8

  • eBook Packages: Springer Book Archive

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