Normal Heart and Vessels
Our current understanding of the molecular structure of heart and vessels has considerably increased over the last ten years. Most, nearly all, of the genes coding for cardiovascular proteins have been cloned and sequenced and, in addition, the amino acid composition of the cardiovascular proteins that had not previously been sequenced, is now known. Informations has also been obtained from genomic sequences that concern the regulatory parts of the genes, and subsequently their potential physiological regulation. Obviously such a chapter may constitute an entire book. A selection has therefore been made amongst an enormous mass of information in order to retain the data which has a potential interest in terms of physiological and pharmacological properties. This is the reason why the chapter has been presented in terms of structure/function relationships.
KeywordsSarcoplasmic Reticulum Myosin Heavy Chain Thin Filament Thick Filament Myosin Heavy Chain Isoforms
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