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In Vitro Expansion of Hematopoietic Cells for Clinical Application

  • Stephen G. Emerson
  • Bernhard O. Palsson
  • Michael F. Clarke
  • Samuel M. Silver
  • Paul T. Adams
  • Manfred R. Koller
  • Gary Van Zant
  • Susan Rummel
  • R. Douglas Armstrong
  • James Maluta
  • Judith Douville
  • Leslie Paul
Chapter
Part of the Cancer Treatment and Research book series (CTAR, volume 76)

Abstract

The past 15 years have seen a tremendous explosion in our knowledge of the molecular and cellular regulation of hematopoietic differentiation. Launched with the identification and purification of candidate hematopoietic stem cells by Visser et al. in 1984 [1] and the molecular cloning of recombinant human (rH-) granulocyte macrophage-colony stimulating factor (GM-CSF) in 1984 [2], the field of hematopoiesis has transformed from a specialized garden industry to a position of dominance in molecular biology, developmental genetics, and cancer biology. While many mysteries remain, many of the fundamentals appear to be in view, or at least within reach.

Keywords

Stem Cell Hematopoietic Cell Umbilical Cord Blood Allogeneic Bone Marrow Transplantation Autologous Bone Marrow Transplant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Stephen G. Emerson
  • Bernhard O. Palsson
  • Michael F. Clarke
  • Samuel M. Silver
  • Paul T. Adams
  • Manfred R. Koller
  • Gary Van Zant
  • Susan Rummel
  • R. Douglas Armstrong
  • James Maluta
  • Judith Douville
  • Leslie Paul

There are no affiliations available

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