Food as an Assay Matrix
In the sense used here, the matrix is the complex of food components that is to be analysed for the presence of the target analyte. In any assay procedure, not just those based on antibody binding, the food matrix can interfere and produce an erroneous result. When assaying for the presence or absence of a target, food has the potential to give ‘false-positive’ results, i.e. those that are positive when the true result is negative, and also the converse ‘false-negative’ results. This, of course, begs the question: What is the ‘true’ result? As mentioned previously, this can only be assessed in relation to a standard, well-tried method, which may in itself be less than perfect.
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