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Spinal Seizures in Ammonia Intoxication

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Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 368))

Abstract

Ammonia intoxication is well known to produce seizures (1). These seizures may be cortical or spinal in origin (1,2,3,4,5). Because ammonia predominantly increases the excitability of the spinal cord (1,2), most seizures are probably spinal in origin. The pathophysiology of cortical and spinal seizures induced by ammonia intoxication is not well understood. In addition, it has not been investigated when these spinal seizures occur during the course of ammonia intoxication. This study attempts to elucidate these little understood issues.

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Authors and Affiliations

  1. Neurology, VA Medical Center, Depts. Neurology and Physiology, University of Minnesota, Minneapolis, 55417, USA

    W. Raabe

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  1. W. Raabe
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Editors and Affiliations

  1. Instituto de Investigaciones Citologicas de la F. I. B., Valencia, Spain

    Vicente Felipo  & Santiago Grisolia  & 

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Raabe, W. (1994). Spinal Seizures in Ammonia Intoxication. In: Felipo, V., Grisolia, S. (eds) Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity. Advances in Experimental Medicine and Biology, vol 368. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1989-8_6

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  • DOI: https://doi.org/10.1007/978-1-4615-1989-8_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5820-6

  • Online ISBN: 978-1-4615-1989-8

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