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Basic Biology of Pig Fetal Pancreas and Its Use as an Allograft

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Fetal Islet Transplantation

Abstract

Diabetes is a chronic disorder of metabolism, which has the potential to result in the development of microvascular complications, such as retinopathy and nephropathy, many years after the onset of the disease process. This is particularly relevant to insulin-dependent diabetes, which affects the young, with blindness and renal failure occurring early in life, rather than at an advanced age, which can occur in non-insulin dependent diabetes. Until insulin dependent diabetes can be prevented, or cured by means of gene transfer, pancreatic transplantation is probably the most likely means at our disposal to normalize blood glucose levels, and thus prevent the occurrence of complications.

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Tuch, B.E. et al. (1995). Basic Biology of Pig Fetal Pancreas and Its Use as an Allograft. In: Peterson, C.M., Jovanovic-Peterson, L., Formby, B. (eds) Fetal Islet Transplantation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1981-2_5

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  • DOI: https://doi.org/10.1007/978-1-4615-1981-2_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5816-9

  • Online ISBN: 978-1-4615-1981-2

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