Differential Expression of ß-Lactoglobulin Alleles A and B in Dairy Cattle

  • R. J. Wilkins
  • H. W. Davey
  • T. T. Wheeler
  • C. A. Ford

Abstract

Two allelic variants of the whey protein ß-lactoglobulin gene are commonly found in dairy cattle. Interestingly, some 20 to 40% more of the A than the B variant protein is produced in milk. We report here our efforts to elucidate the basic molecular mechanisms responsible for the differential expression of the two ß-lactoglobulin alleles.

Keywords

Lactate Oligomer 

References

  1. Ford, CA., 1993, Gene expression of the A and B variants of ß-lactoglobulin, MSc Thesis, The University of Waikato, New Zealand.Google Scholar
  2. Ford, C.A., Connett, M.B. and Wilkins, R.J., 1993, ß-lactoglobulin expression in bovine mammary tissue, Proc. NZ Soc. Anim. Prod 53:167.Google Scholar
  3. Watson, C.J., Gordon, K.E., Robertson, M. and Clark, A.J., 1991, Interaction of DNA-binding proteins with a milk protein gene promoter in vitro identification of a mammary gland-specific factor, Nucl. Acids Res 19:6603.PubMedCrossRefGoogle Scholar
  4. Wilkins, R.J., 1993, Allele specific oligonucleotide probes for mRNA, Biotech 14:352.Google Scholar

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • R. J. Wilkins
    • 1
    • 2
  • H. W. Davey
    • 1
  • T. T. Wheeler
    • 1
  • C. A. Ford
    • 2
  1. 1.AgResearch, Ruakura Agricultural CentreHamiltonNew Zealand
  2. 2.Centre for Research in Animal BiologyUniversity of WaikatoHamiltonNew Zealand

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