Abstract
Aldehyde dehydrogenase (AlDH) is an NAD+-dependent enzyme that is widely distributed through many different species, including both eukaryotes and prokaryotes. In animals, aldehyde dehydrogenases are found in a number of different bodily locations where they exist as several distinct isozymes. These enzymes share the general role of detoxification of aldehydes (Jakoby and Ziegler, 1990) but the individual isozymes show differences in specificity and reactivity that suggest they may have additional, more specialised, roles.
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Baker, H.M., Brown, R.L., Dobbs, A.J., Kitson, K.E., Kitson, T.M., Baker, E.N. (1995). Crystallization of Sheep Liver Cytosolic Aldehyde Dehydrogenase in a form Suitable for High Resolution X-Ray Structural Analysis. In: Weiner, H., Holmes, R.S., Wermuth, B. (eds) Enzymology and Molecular Biology of Carbonyl Metabolism 5. Advances in Experimental Medicine and Biology, vol 372. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1965-2_9
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DOI: https://doi.org/10.1007/978-1-4615-1965-2_9
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