Molecular Biology of Tf

  • Thomas S. Edgington
  • Wolfram Ruf
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)


About half of deaths and major morbidity of the populations of the advanced Western nations have as the underlying or penultimate process vascular pathology associated with and attributable to activation of the coagulation-thrombogenic molecular pathways. Whereas the general principles, and majority of molecular players in the thrombogenic pathways are known and biochemically characterized, the major challenge continues to be safe and effective prevention and intervention in coronary, cerebral and other thrombotic diseases.


Tissue Factor Disseminate Intravascular Coagulation Tissue Factor Pathway Inhibitor Initiation Complex Tissue Factor Expression 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Thomas S. Edgington
    • 1
  • Wolfram Ruf
    • 1
  1. 1.The Department of Immunology The Scripps Research InstituteVascular Cell Molecular Biology UnitLa JollaUSA

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