Perienteral Chloragogen Tissue and its Role in Defense in Lumbricid Worms

  • Petr Sima
  • Martin Bilej
  • Jaroslav Slipka
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 371)


Annelids are able to express a type of adaptive immunity. The main work in that respect has been done on lumbricids in which the perienteral chloragogenic tissue seems to be the only precursor organ that produces free defense cells and humoral defense factors. In this work we demonstrate morphologically a perivascular localization of phagocytozed radioactively-labeled particles inside the typhlosole, an enteric organ considered as an analog of the gut-associated lymphoid structures of vertebrates. The inflammation-like reactions in the typhlosole after challenge by endotoxin are documented histologically.


Precursor Organ Coelomic Fluid3 Coelomic Cavity Enteric Organ Dorsal Vein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    M. Bilej, P. Sima, and J. Slipka, Immunol Lett. 32: 181 (1992).PubMedCrossRefGoogle Scholar
  2. 2.
    E. Stein, R. R. Avtalion, and E. L. Cooper, J. Morph. 153: 467 (1977).PubMedCrossRefGoogle Scholar
  3. 3.
    L. Tuckova, J. Rejnek, P. Sima, and R. Ondrejova, Develop. Compar. Immunol 10: 181 (1986).CrossRefGoogle Scholar
  4. 4.
    P. Valembois, P. Roch, and M. Lassegues, in: “Immunity in Invertebrates”, M. Brehelin, ed., Springer-Verlag, Berlin (1986).Google Scholar

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Petr Sima
    • 1
  • Martin Bilej
    • 1
  • Jaroslav Slipka
    • 2
  1. 1.Department of Immunology Institute of MicrobiologyCzech Academy of Sciences PragueCzech Republic
  2. 2.Faculty of MedicineCharles UniversityPilsenCzech Republic

Personalised recommendations