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Antigen Presentation by a Mouse Duodenal Epithelial Cell Line (Mode-K)

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Advances in Mucosal Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 371))

Abstract

Studies on the immunological aspects of lymphoepithelial interactions in the intestine have been hampered by the difficulty to maintain enterocytes viable in vitro after isolation from the mucosa. We have recently established1 a mouse duodenal epithelial cell line, MODE-K, immortalized by the SV40 large T antigen, which retained phenotypical characteristics of normal enterocytes. We have examined the immunologic function of MODE-K cells in antigen presentation to a specific class II-restricted T cell hybridoma.

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References

  1. K. Vidal, I. Grosjean, C. Gespach, J. P. Revillard, and D. Kaiserlian, (submitted).

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Author information

Authors and Affiliations

  1. Unitéd Immunologie et de Stratégie Vaccinale, Institut Pasteur, Avenue Tony-Garnier, 69365, Lyon Cedex 07, France

    Karine Vidal, Isabelle Grosjean & Dominique Kaiserlian

Authors
  1. Karine Vidal
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  2. Isabelle Grosjean
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  3. Dominique Kaiserlian
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Editor information

Editors and Affiliations

  1. University of Alabama at Birmingham, Birmingham, Alabama, USA

    Jiri Mestecky , Michael W. Russell , Susan Jackson  & Suzanne M. Michalek , ,  & 

  2. Academy of Sciences of the Czech Republic, Prague, Czech Republic

    Helena Tlaskalová-Hogenová  & Jaroslav Šterzl  & 

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© 1995 Springer Science+Business Media New York

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Vidal, K., Grosjean, I., Kaiserlian, D. (1995). Antigen Presentation by a Mouse Duodenal Epithelial Cell Line (Mode-K). In: Mestecky, J., Russell, M.W., Jackson, S., Michalek, S.M., Tlaskalová-Hogenová, H., Šterzl, J. (eds) Advances in Mucosal Immunology. Advances in Experimental Medicine and Biology, vol 371. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1941-6_46

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  • DOI: https://doi.org/10.1007/978-1-4615-1941-6_46

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5796-4

  • Online ISBN: 978-1-4615-1941-6

  • eBook Packages: Springer Book Archive

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