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Advances in Mucosal Immunology pp 145–147Cite as

A Role for Antigen in the Evolution of Gastrointestinal Malt-Type B Cell Lymphoma

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 371))

Abstract

Low grade B cell lymphomas of mucosa associated lymphoid tissue (MALT) are a discrete group of malignancies occurring most commonly at mucosal sites which are normally devoid of lymphoid tissue.1 These sites have been shown to acquire reactive lymphoid tissue resembling normal MALT seen in the Peyer‘s patch of the terminal ileum1,2 before or at the onset of lymphoma development. Several characteristic features such as the persistence of follicular dendritic cells, the presence of reactive follicles and a range in cellular morphology within these ‘MALT-type lymphomas suggest that they may arise in the course of an immune response to antigen.1,3

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References

  1. P. G. Isaacson and J. Spencer, Histopathology, 11: 445 (1987).

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  2. J. Spencer, T. Finn and P. G. Isaacson, Gut, 27: 405 (1986).

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  3. J. K. C. Chan, C. S. Ng, and P. G. Isaacson, Am. J. Pathol., 136: 1153 (1990).

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  4. T. Hussell and P. G. Isaacson, J. Spencer, Am. J. Pathol, (in press).

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  5. T. Hussel and P. G. Isaacson, J. Spencer, J. Pathol, (in press).

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  6. E. Hyjeck and W. J. Smith, P. G. Isaacson, Human Pathol, 19: 766 (1988).

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  7. E. Hyjeck and P. G. Isaacson, Human Pathol., 19: 1315 (1988).

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Author information

Authors and Affiliations

  1. Department of Histopathology, UCMSM, University Street, London, WC1E 6JJ, UK

    Tracy Hussell, P. G. Isaacson & Jo Spencer

Authors
  1. Tracy Hussell
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  2. P. G. Isaacson
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  3. Jo Spencer
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Editor information

Editors and Affiliations

  1. University of Alabama at Birmingham, Birmingham, Alabama, USA

    Jiri Mestecky , Michael W. Russell , Susan Jackson  & Suzanne M. Michalek , ,  & 

  2. Academy of Sciences of the Czech Republic, Prague, Czech Republic

    Helena Tlaskalová-Hogenová  & Jaroslav Šterzl  & 

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© 1995 Springer Science+Business Media New York

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Hussell, T., Isaacson, P.G., Spencer, J. (1995). A Role for Antigen in the Evolution of Gastrointestinal Malt-Type B Cell Lymphoma. In: Mestecky, J., Russell, M.W., Jackson, S., Michalek, S.M., Tlaskalová-Hogenová, H., Šterzl, J. (eds) Advances in Mucosal Immunology. Advances in Experimental Medicine and Biology, vol 371. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1941-6_28

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  • DOI: https://doi.org/10.1007/978-1-4615-1941-6_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5796-4

  • Online ISBN: 978-1-4615-1941-6

  • eBook Packages: Springer Book Archive

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