The Migration of Peritoneal Cells Towards the Gut

  • Taede Sminia
  • Marsetyawan Soesatyo
  • Mohammad Ghufron
  • Theo Thepen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 371)


Peritoneal cells form a heterogeneous cell population. In the rat about 70% of them are macrophages, 20% consist of granulocytes and mast cells, and the rest comprise dendritic cells and lymphocytes.1 In microbial infections and after antigen administration, quantitative and qualitative changes occur within these peritoneal cell populations. Peritoneal macrophages efficiently handle antigen locally and transport it via the lymphatics to lymphoid tissues. There are at least two different routes for transport of antigen by peritoneal cells: first, via the lymphatics to the draining lymph nodes12, and second, across the diaphragm directly to the lung interstitium.10


Peritoneal Macrophage Mesenteric Lymph Node Drain Lymph Node Fluorescent Cell Peritoneal Cell 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Taede Sminia
    • 1
  • Marsetyawan Soesatyo
    • 1
  • Mohammad Ghufron
    • 1
  • Theo Thepen
    • 1
  1. 1.Department of Cell Biology, Section HistologyVrije UniversiteitAmsterdamThe Netherlands

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