Abstract
Neurons in the adult brain are capable of receiving and giving new synapses after injury (Raisman, 1969) or transplantation (Zhou et al., 1990). These events only occur in grey matter. When nerve fibres are cut in white matter tracts, they fail to regenerate. However, cut fibres can be induced to regenerate all the way to form functional contacts with their targets by the use of peripheral nerve grafts (Vidal-Sanz et al., 1987).
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Berry M, Rees L, Hall S, Yiu P, Sievers J (1988): Optic axons regenerate into sciatic nerve isografts only in the presence of Schwann cells. Brain Res Bull 20: 223–231.
Brook GA, Lawrence JM, Raisman G (1993): Morphology and migration of cultured Schwann cells transplanted into the fimbria and hippocampus in adult rats. Glia 9: 292–304.
Brook GA, Lawrence JM, Shah B, Raisman G (1994): Extrusion transplantation of Schwann cells into the adult rat thalamus induces directional host axon growth. Exp Neurol 125: 1–13.
Butt AM, Ransom BR (1993): Morphology of astrocytes and oligodendrocytes during development in the intact rat optic nerve. J Comp Neurol 338: 141–158.
Davies SJA, Field PM, Raisman G (1993): Long fibre growth by axons of embryonic mouse hippocampal neurons micro-transplanted into the adult rat fimbria. Eur J Neurosci 5: 95–106.
Davies SJA, Field PM, Raisman G (1994): Long interfascicular axon growth from embryonic neurons transplanted into adult myelinated tracts. J Neurosci 14: 1596–1612..
Li Y, Raisman G (1993): Long interfascicular axon growth from embryonic mouse hippocampal neurons transplanted into the myelinated corticospinal tracts and dorsal columns of immunosuppressed adult rat hosts. Brain Res 629: 115–127.
Li Y, Raisman G (1994): Schwann cells induce sprouting in motor and sensory axons in the adult rat spinal cord. J Neurosci 14: 4050–4063.
Neuberger TJ, Cornbrooks CJ, Kromer LF (1992): Effects of delayed transplantation of cultured Schwann cells on axonal regeneration from central nervous system cholinergic neurons. J Comp Neurol 315: 16–33.
O’Leary DDM, Bicknese AR, De Carlos JA, Heffner CD, Koester SI, Kutka Lt, Terashima T (1990): Target selection by cortical axons: alternative mechanisms to establish axonal connections in the developing brain. Cold Spring Harbor Symp Quant 55: 453–468.
Raisman G (1969): Neuronal plasticity in the septal nuclei of the adult rat. Brain Res 14: 25–48.
Schwab ME, Kapfhammer JP, Bandtlow CE (1993): Inhibitors of neurite growth. Annu Rev Neurosci 16: 565–595.
Suzuki M, Raisman G (1992): The glial framework of central white matter tracts: Segmented rows of contiguous interfascicular oligodendrocytes and solitary astrocytes give rise to a continuous meshwork of transverse and longitudinal processes in the adult rat fimbria. Glia 6: 222–235.
Suzuki M, Raisman G (1994): Multifocal pattern of postnatal development of the macroglial framework of the rat fimbria. Glia (in press).
Vidal-Sanz M, Bray GM, Villegas-Pérez MP, Thanos S, Aguayo At (1987): Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat. J Neurosci 7: 2894–2909.
Zhou CF, Li Y, Morris RJ, Raisman G (1990): Accurate reconstruction of three complementary laminar afferents to the adult hippocampus by embryonic neural grafts. Neurosci Res Suppl 13: S43–S53.
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© 1995 Springer Science+Business Media New York
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Raisman, G. (1995). Incorporation of Cells into Adult Fibre Tracts. In: Juurlink, B.H.J., Krone, P.H., Kulyk, W.M., Verge, V.M.K., Doucette, J.R. (eds) Neural Cell Specification. Altschul Symposia Series, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1929-4_20
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DOI: https://doi.org/10.1007/978-1-4615-1929-4_20
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