Melatonin and Sleep

  • J. David Parkes
Part of the NATO ASI Series book series (NSSA, volume 277)


The purpose of this review is two-fold. First, as an introduction to the role of melatonin in the circadian biological rhythm of sleeping and waking, I will discuss the normal sleep-wake cycle of man. Important issues here include the basic organisation of circadian mechanisms of sleeping and waking, the normal physiology of sleep and the biochemical systems involved. Sleep disorders in man and their present pharmacological management will be stressed, because of their importance in relation to circadian rhythm and melatonin research..


Daytime Sleepiness Obstructive Sleep Apnoea Total Sleep Time NREM Sleep Blind Subject 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • J. David Parkes
    • 1
  1. 1.King’s College Hospital and Institute of PsychiatryUniversity Department of NeurologyLondonUK

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