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Chiral Hydrogenation of Estrone and Estrone-3-Methyl Ether

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Chiral Reactions in Heterogeneous Catalysis

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Abstract

We have previously studied the use of enantiomeric chiral reducing agents in solution to control the direction of the hydrogenation of the keto group of estrone and estrone-3-methyl ether [1]. The complex catalysts chiral hydrosilane-rhodium-( +)- or (-)-DIOP or (+)- or (-)-BINAP allowed different stereoselectivities in the formation of the 17α- and 17β-alcohols.

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References

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Author information

Authors and Affiliations

  1. Department of Organic Chemistry, József Attila University, Dóm tér 8, H-6720, Szeged, Hungary

    Gy Göndös, Gy Wittmann & M. Bartók

  2. Faculty of Medicine, Memorial University of Newfoundland, St. John’s, A1B 3V6, NF, Canada

    J. C. Orr

Authors
  1. Gy Göndös
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  2. Gy Wittmann
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  3. M. Bartók
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  4. J. C. Orr
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Editor information

Editors and Affiliations

  1. CERIA/Meurice Institute, Brussels, Belgium

    Georges Jannes  & Vincent Dubois  & 

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© 1995 Springer Science+Business Media New York

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Göndös, G., Wittmann, G., Bartók, M., Orr, J.C. (1995). Chiral Hydrogenation of Estrone and Estrone-3-Methyl Ether. In: Jannes, G., Dubois, V. (eds) Chiral Reactions in Heterogeneous Catalysis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1909-6_9

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  • DOI: https://doi.org/10.1007/978-1-4615-1909-6_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5780-3

  • Online ISBN: 978-1-4615-1909-6

  • eBook Packages: Springer Book Archive

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