Asymmetric Hydrogenation of Ethyl Pyruvate Using Ptcontaining Zeolites Modified With (-)-Cinchonidine
Platinum loaded, (-)-cinchonidine modified zeolites of the types Y, ZSM-35, β and ZSM-5 manifest high catalytic activity for the asymmetric hydrogenation of ethyl pyruvate to ethyl lactate. The catalysts based on Y and ZSM-35 zeolites show the highest enantioselectivity. To obtain the highest reaction rates and the optical yields the Pt content should be around 5 wt%
Enantiomeric excess is strongly influenced by the type of solvent used and can be raised from 60% ee. to 80% ee. merely by varying the solvents.
KeywordsNickel Ethyl Acetone Platinum Zeolite
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