Asymmetric Hydrogenation of Ethyl Pyruvate Using Ptcontaining Zeolites Modified With (-)-Cinchonidine

  • W. Reschetilowski
  • U. Böhmer
  • J. Wiehl


Platinum loaded, (-)-cinchonidine modified zeolites of the types Y, ZSM-35, β and ZSM-5 manifest high catalytic activity for the asymmetric hydrogenation of ethyl pyruvate to ethyl lactate. The catalysts based on Y and ZSM-35 zeolites show the highest enantioselectivity. To obtain the highest reaction rates and the optical yields the Pt content should be around 5 wt%

Enantiomeric excess is strongly influenced by the type of solvent used and can be raised from 60% ee. to 80% ee. merely by varying the solvents.


Nickel Ethyl Acetone Platinum Zeolite 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. [1]
    S. Akabori, Y. Izumi, Y. Fujii and S. Sakurai, J. Chem. Soc. Japan, Pure Chem. Sec. 77 (1956) 1374.Google Scholar
  2. [2]
    I. Yasumori, M. Yokozeki and Y. Inoue, Faraday Disc. Chem. Soc. 72 (1981), 385.CrossRefGoogle Scholar
  3. [3]
    T. Osawa, T. Harada and A. Tai, J. Catal. 121 (1990) 7.CrossRefGoogle Scholar
  4. [4]
    Y. Orito, S. Imai, S. Niwa and Nguyen G.-H., J. Synth. Org. Chem. Jpn. 37 (1979) 173.CrossRefGoogle Scholar
  5. [5]
    J.T. Wehrli, A. Baiker, D.M. Monti, H.U. Blaser and H.P. Jalett, J. Mol. Catal. 57 (1989) 245.CrossRefGoogle Scholar
  6. [6]
    H.U. Blaser, H.P. Jalett and J. Wiehl, J. Mol. Catal. 68 (1991) 215.CrossRefGoogle Scholar
  7. [7]
    J.L. Margitfalvi, B. Minder, E. Talás, L. Botz and A. Baiker, Stud. Surf. Sci. Catal. 75C (1993) 2471.CrossRefGoogle Scholar
  8. [8]
    R.M. Dessau, US Patent 4 554 262 (1985).Google Scholar
  9. [9]
    J. Weitkamp, Stud. Surf. Sci. Catal. 65 (1991) 21.CrossRefGoogle Scholar
  10. [10]
    A. Corma, M. Iglesias, C. del Pino, and F. Sánchez, Stud. Surf. Sci. Catal. 75C (1993) 2293.CrossRefGoogle Scholar
  11. [11]
    W. Reschetilowski, U. Böhmer, Proc. DGMK-Conference “Selective Hydrogenations and Dehydrogenations”, Kassel, Germany, 1993, p. 275.Google Scholar

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • W. Reschetilowski
    • 1
  • U. Böhmer
    • 1
  • J. Wiehl
    • 2
  1. 1.Karl-Winnacker-Institut der DECHEMA e.VFrankfurt am MainGermany
  2. 2.W.C. Heraeus GmbHHanauGermany

Personalised recommendations