Asymmetric Hydrogenation of Ethyl Pyruvate Using Ptcontaining Zeolites Modified With (-)-Cinchonidine
Platinum loaded, (-)-cinchonidine modified zeolites of the types Y, ZSM-35, β and ZSM-5 manifest high catalytic activity for the asymmetric hydrogenation of ethyl pyruvate to ethyl lactate. The catalysts based on Y and ZSM-35 zeolites show the highest enantioselectivity. To obtain the highest reaction rates and the optical yields the Pt content should be around 5 wt%
Enantiomeric excess is strongly influenced by the type of solvent used and can be raised from 60% ee. to 80% ee. merely by varying the solvents.
KeywordsEnantiomeric Excess Initial Reaction Rate High Reaction Rate Ethyl Pyruvate Optical Yield
Unable to display preview. Download preview PDF.
- S. Akabori, Y. Izumi, Y. Fujii and S. Sakurai, J. Chem. Soc. Japan, Pure Chem. Sec. 77 (1956) 1374.Google Scholar
- R.M. Dessau, US Patent 4 554 262 (1985).Google Scholar
- W. Reschetilowski, U. Böhmer, Proc. DGMK-Conference “Selective Hydrogenations and Dehydrogenations”, Kassel, Germany, 1993, p. 275.Google Scholar