Retinal Degeneration in Rats Induced by Vitamin E Deficiency

  • E. El-Hifnawi
  • H.-J. Hettlich
  • C. Falk


The biological function of vitamin E as a lipid antioxidant has been a topic of investigations for over fifty years. Since the discovery of antioxidant activity, several functions of vitamin E have been elucidated and its role in various vertebrate organs has been examined and discussed. Numerous studies have demonstrated that α-tocopherol (vitamin E) is related to reproduction and that its deficiency results in sterility (White et al. 1978). Furthermore, the role of vitamin E in oxygen metabolism and membrane function as a protector against free radical oxidation has been documented in several studies (Lucy 1978; McCayetal. 1978).


Retinal Pigment Epithelium Retinal Pigment Epithelium Cell Outer Segment Photoreceptor Cell Deficient Diet 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • E. El-Hifnawi
    • 1
  • H.-J. Hettlich
    • 1
  • C. Falk
    • 1
  1. 1.Department of OphthalmologyUniversity of LübeckLübeckGermany

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