The Role of Vasopressin and Angiotensin II in the Hemodynamic Response to Dynamic Exercise

  • J. David Symons
  • Charles L. Stebbins
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 381)


The cardiovascular response to dynamic exercise is characterized by increases in blood pressure, myocardial contractility, and heart rate (Mitchell, 1990). In addition, cardiac output is redistributed such that blood flow is reduced in the renal and splanchnic circulations,while it is greatly increased to the heart and contracting skeletal muscles (Armstrong et al, 1987). Although central neural mechanisms (i.e. central command) and reflexes originating in working skeletal muscles are largely responsible for these alterations (Mitchell, 1990), hormones released during physical activity also may contribute to or modulate the cardiovascular response to dynamic exercise.


Angiotensin Converting Enzyme Myocardial Blood Flow Systemic Vascular Resistance Receptor Blockade Hemodynamic Response 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • J. David Symons
    • 1
    • 2
  • Charles L. Stebbins
    • 1
  1. 1.Department of Internal Medicine, Division of Cardiovascular Medicine and Department of Human PhysiologyUniversity of California, DavisDavisUSA
  2. 2.Department of Cardiovascular PharmacologyAlliance Pharmaceutical CorporationSan DiegoUSA

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