Abstract
Evidence exists that ultraviolet radiation, drugs, chemicals, and inherent mechanisms directly or via the generation of inflammatory mediators and oxygen free radicals can exert effects on DNA damage and repair1,2,3. Thus the evaluation of DNA damage and the investigation of factors influencing its quantification are of prime interest for pharmaceutical, clinical and basic scientific reasons4,5,6. Previous approaches towards the quantification of DNA damage in lens epithelial cells lacked a systematic analysis of individual factors such as cell origin, cell cycle phase, Go synchronization, and the interaction between these factors.
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Breipohl, W. et al. (1995). The Comet Assay: A Reliable and Sensitive Method for the Documentation of UV-B Induced DNA Damage. In: Weisse, I., Hockwin, O., Green, K., Tripathi, R.C. (eds) Ocular Toxicology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1887-7_40
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DOI: https://doi.org/10.1007/978-1-4615-1887-7_40
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