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Hyperbaric Oxygen Therapy Induces a Lenticular Myopic Shift Even with Shorter Treatment Protocol: A Preliminary Report

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Ocular Toxicology

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Abstract

Hyperbaric oxygen (HBO) is currently a widely accepted treatment modality for a variety of disorders. Previous reports have shown that prolonged treatment with HBO induces a myopic shift in refraction. We evaluated the frequency, duration and reversibility of myopia in patients who were undergoing HBO with the current shorter protocols (up to 36 treatments). Patients were followed at two medical centers (South Carolina, USA and Devon, England). Four patients, analyzed retrospectively in South Carolina, had blurred vision after 8 to 15 treatments, and two were documented to have a myopic shift. Twenty-nine patients (5 in South Carolina and 26 in Devon) were followed prospectively. Eleven of the prospective group developed a myopic shift in refraction. Maximum shifts were -3.00 diopters. Of the 11 patients, 5 returned to baseline, and 6 were lost to follow-up. The duration of myopic shift has been less than 3 months. No other ocular changes have been noted during the course of HBO. Our findings from two separate institutions indicate that HBO therapy can induce a transient lenticular myopia even with shorter protocols.

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Authors and Affiliations

  1. Department of Ophthalmology, The University of South Carolina School of Medicine, Columbia, SC, USA

    S. M. Johnson & R. C. Tripathi

  2. Department of Hyperbaric Medicine, Richland Memorial Hospital, Columbia, SC, USA

    P. J. Bryson

  3. The South Western Hyperbaric Medical Centre, Devon, UK

    R. Clark

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  1. S. M. Johnson
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  2. P. J. Bryson
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  3. R. Clark
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  4. R. C. Tripathi
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Editors and Affiliations

  1. Boehringer Ingelheim KG, Ingelheim, Germany

    Ingo Weisse

  2. University of Bonn, Bonn, Germany

    Otto Hockwin

  3. Medical College of Georgia, Augusta, Georgia, USA

    Keith Green

  4. South Carolina Eye Institute, Columbia, South Carolina, USA

    Ramesh C. Tripathi

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Johnson, S.M., Bryson, P.J., Clark, R., Tripathi, R.C. (1995). Hyperbaric Oxygen Therapy Induces a Lenticular Myopic Shift Even with Shorter Treatment Protocol: A Preliminary Report. In: Weisse, I., Hockwin, O., Green, K., Tripathi, R.C. (eds) Ocular Toxicology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1887-7_26

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  • DOI: https://doi.org/10.1007/978-1-4615-1887-7_26

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5769-8

  • Online ISBN: 978-1-4615-1887-7

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