Abstract
Protein N- or O-linked and lipid-linked complex-type oligosaccharide chains are typically based on Ga1β1→4GlcNAc (N-acetyllactosamine, lacNAc) units that serve as backbone structural elements which are built on a core structure (figure 1). Sometimes they contain repeats of these lacNAc units to form so called polylactosaminoglycan chains. These chains are the carriers of terminal, functionally active carbohydrate epitopes such as the sialyl-Lewisx and the oligomeric Lewisx structure. These terminal structures often confer specific biological functions on the glycoconjugates carrying them.
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Van den Eijnden, D.H., Neeleman, A.P., Van der Knaap, W.P.W., Bakker, H., Agterberg, M., Van Die, I. (1995). Control and Function of Complex-Type Oligosaccharide Synthesis. In: Alavi, A., Axford, J.S. (eds) Glycoimmunology. Advances in Experimental Medicine and Biology, vol 376. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1885-3_5
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DOI: https://doi.org/10.1007/978-1-4615-1885-3_5
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