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The Decidual Hormones and Their Role in Pregnancy Recognition

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Endocrinology of Embryo-Endometrium Interactions

Part of the book series: Reproductive Biology ((RBIO))

Abstract

How does the mother recognize the presence of the blastocyst and adjust to provide the right milieu for the embryo to implant, to grow, and to remain in a safe uterine environment until able to survive outside the womb? The answer to this question, as discussed by Dr. Mori and Kanzaki in another chapter, appears to differ in different species. However one common denominator to all species is the necessity to maintain adequate levels of ovarian steroids in the maternal circulation and to rapidly change the uterine environment so that contact between mother and fetus becomes possible without damage to the mother or rejection of the fetus.

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References

  • Barrett AJ, Starkey PM, 1973. The interaction of α2-macroglobulin with proteinase. Biochem. J. 133:709–724.

    PubMed  CAS  Google Scholar 

  • Basuray R, Gibori G, 1980. Luteotropic action of the decidual tissue in the pregnant rat. Biol. Reprod. 23:507–512.

    Article  PubMed  CAS  Google Scholar 

  • Basuray R, Jaffe RC, Gibori G, 1983. Role of decidual luteotropin and prolactin in the control of luteal cell receptors for estradiol. Biol. Reprod. 28:551–556.

    Article  PubMed  CAS  Google Scholar 

  • Chu CT, Rubenstein DS, Engheld JJ, Pizzo SV, 1991. Mechanism of insulin incorporation into a 2 macroglobulin: implication for the study of peptide and growth factor binding. Biochemistry 30:1551–1560.

    Article  PubMed  CAS  Google Scholar 

  • Croze F, Kennedy TG, Schroeder IC, Friesen HG, 1990. Expression of rat prolactin-like protein-B in deciduoma of pseudopregnant rat and in decidua during early pregnancy. Endocrinology 127:2665-

    Article  PubMed  CAS  Google Scholar 

  • Gaddy-Kurten D, Richards JS, 1989. Regulation of a 2 macroglobulin by luteinizing hormone and prolactin during cell differentiation in the rat ovary. Mol. Endocrinol. 5:1280–1291.

    Article  Google Scholar 

  • Gibori G, 1993. Decidual hormones in pregnancy. Endocrinology 130: Abstract #20.

    Google Scholar 

  • Gibori G, Basuray R, McReynolds B, 1981. Luteotropic role of the decidual tissue in the rat: dependency on intraluteal estradiol. Endocrinology 108:2060–2066.

    Article  PubMed  CAS  Google Scholar 

  • Gibori G, Jayatilak PG, Khan I, Rigby B, Puryear T, Nelson S, Herz Z, 1987. Decidual luteotropin secretion and action: Its role in pregnancy maintenance in the rat. In: Mahesh VB, Dhindsa DS, Anderson E, Kalra SP (eds.), Regulation of Ovarian and Testicular function. Plenum Press, New York, pp. 379–397.

    Chapter  Google Scholar 

  • Gibori G, Kalison B, Basuray R, Rao MC, Hunzicker-Dunn M, 1984. Endocrine role of the of the decidual tissue: Decidual luteotropin regulation of luteal adenylyl cyclase, cyclase activity, luteinizing hormone receptors, and steroidogenesis. Endocrinology 115:1157–1163.

    Article  PubMed  CAS  Google Scholar 

  • Gibori G, Kalison B, Warshaw, ML, Basuray R. Glaser LA, 1985. Differential action of decidual luteotropin on luteal and follicular production of testosterone and estradiol. Endocrinology 116:1784–1791.

    Article  PubMed  CAS  Google Scholar 

  • Gibori G, Rothchild I, Pepe GJ, Morishige WK, Lam P, 1974. Luteotropic action of the decidual tissue in the rat. Endocrinology 95:1113–1118.

    Article  PubMed  CAS  Google Scholar 

  • Gu Y, Jayatilak PG and Gibori G, 1992a. Cell specific expression and binding of decidual luteotropin in the rat decidua. Biol. Reprod. 467. Suppl. 1:140, Abstract #43.

    Google Scholar 

  • Gu Y, Jayatilak PG, Parmer TG, Gauldie J, Fey GH and Gibori G, 1992b. a 2-Macroglobulin expression in the mesometrial decidua and its regulation by decidual luteotropin and prolactin. Endocrinology, 131:1321–1328.

    Article  PubMed  CAS  Google Scholar 

  • Gu Y, Soares MJ and Gibori G, 1993. Rat decidual PRL-related protein gene: Cell specific expression and regulation. Biology of Reproduction 48: Abstract #478.

    Google Scholar 

  • Herz Z, Khan I, Jayatilak PG, Gibori G, 1985. Evidence for the synthesis and secretion of decidual luteotropin: A prolactin-like hormone produced by rat decidual cells. Endocrinology 118:2203–2209.

    Article  Google Scholar 

  • Huang SS, O’Grady P, Huang JS, 1988. Human transforming growth factor β — a 2-macroglobulin complex is a latent form of transforming growth factor β. J. Biol. Chem. 264:7210–7216.

    Google Scholar 

  • Jayatilak PG and Gibori G, 1986. Ontogeny of prolactin receptors in rat decidual tissue: Binding by locally produced prolactin-like hormone. J. Endocrinol. 110:115–121.

    Article  PubMed  CAS  Google Scholar 

  • Jayatilak PG, Glaser LA, Basuray R, Kelly PA, Gibori G, 1985. Identification and partial characterization of a prolactin-like hormone produced by the rat decidual tissue. Proc. Natl. Acad. Sci. USA 82:217–221.

    Article  PubMed  CAS  Google Scholar 

  • Jayatilak PG, Glaser LA, Warshaw ML, Herz Z, Gruber JR, Gibori G, 1984. Relationship between luteinizing hormone and decidual luteotropin in the maintenance of luteal steroidogenesis. Biol. Reprod. 31:556–564.

    Article  PubMed  CAS  Google Scholar 

  • Jayatilak PG, Puryear TK, Herz Z, Fazleabas, Gibori G, 1989. Protein secretion by mesometrial and antimesometrial rat decidual tissue: Evidence for differential gene expression. Endocrinology 125:659–666.

    Article  PubMed  CAS  Google Scholar 

  • Kaiser M, Gibori G and Mayo KE, 1990. The rat follistatin gene is highly expressed in decidual tissue. Endocrinology 126:2768–2770.

    Article  PubMed  CAS  Google Scholar 

  • Mather JP, Woodruff TK and Krummen LA, 1992. Paracrine regulation of reproductive function by inhibin and activin. Proc. Soc. Exptl. Biol. Med. 201:1–15.

    CAS  Google Scholar 

  • Roby KF, Deb S, Gibori G, Sziper C, Levan G, Kwok SCM and Soares JM, 1993. Decidual prolactin related proteins: Identification, molecular cloning and characterization. J. Biol. Chem. 268:3136–3142.

    PubMed  CAS  Google Scholar 

  • Rothchild I, Meyer RK, Spielman MA, 1940. A quantitative study of estrogen-progesterone interaction in the formation of placentomata in the castrate rat. Am. J. Physiol. 128:213–217.

    CAS  Google Scholar 

  • Sottrup-Jensen L, 1989. a 2 macroglobulins: Structure, shape, and mechanism of proteinase complex formation. J. Biol. Chem. 264:11539–11542.

    PubMed  CAS  Google Scholar 

  • Xiao S, Findlay JK and Robertson DM, 1990. The effect of bovine activin and follicle-stimulating hormone (FSH) suppressing protein/follistatin on FSH-induced differentiation of rat granulosa cells in vitro. Mol. Cell Endocrinol. 69:1–8.

    Article  PubMed  CAS  Google Scholar 

  • Yochim JM, DeFeo VJ, 1963. Hormonal control of the onset, magnitude and duration of uterine sensitivity in the rat by steroid hormones of the ovary. Endocrinology 72:317–325.

    Article  PubMed  CAS  Google Scholar 

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© 1994 Springer Science+Business Media New York

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Gibori, G. (1994). The Decidual Hormones and Their Role in Pregnancy Recognition. In: Glasser, S.R., Mulholland, J., Psychoyos, A. (eds) Endocrinology of Embryo-Endometrium Interactions. Reproductive Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1881-5_17

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  • DOI: https://doi.org/10.1007/978-1-4615-1881-5_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5766-7

  • Online ISBN: 978-1-4615-1881-5

  • eBook Packages: Springer Book Archive

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