Abstract
Optical imaging (OI) and spectroscopy (OS) use light emitted into scattering media such as human tissue to determine interior structure and chemical content, and have broad application to the field of medicine. Existing medical imaging techniques often are limited in suitability as continuous, noninvasive human monitors, and most do not distinguish between normal, impaired, or dead tissues [1]. Visible and near-infrared light will pass through human tissue in small amounts, and this transmitted or reflected light can be used for constructing in vivo images. Light is nonionizing at many wavelengths, and known to function well as a medical probe for measuring the functional state of tissue. It is believed that such noninvasive optical monitoring techniques potentially offer reduced pain and discomfort associated with medical therapy, improved health outcome, and lowered costs of medical care. Multiple investigators are now studying in vivo optical approaches (including Chance, Kang, Delpy, Arridge, Cope, Hebden, Sevick, Ferrari, Grafton, Alfano, and others). However, due to the high degree of light scattering in tissue, images formed in vivo using optical radiation have been poor, and quantitation rendered nonquantitative by long, irregular photon paths.
Chapter PDF
References
Benaron DA, Stevenson DK. Science 1993;259:1463.
Benaron DA, Lenox M, Stevenson DK. SPIE 1992;1641:35.
Benaron DA, Ho DC, Hahn J, Stevenson DK. Ped Research 1993;33(4):369A.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1994 Springer Science+Business Media New York
About this chapter
Cite this chapter
Benaron, D.A. (1994). Results of Optical Imaging of Brain Pathology. In: Hogan, M.C., Mathieu-Costello, O., Poole, D.C., Wagner, P.D. (eds) Oxygen Transport to Tissue XVI. Advances in Experimental Medicine and Biology, vol 361. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1875-4_28
Download citation
DOI: https://doi.org/10.1007/978-1-4615-1875-4_28
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-5763-6
Online ISBN: 978-1-4615-1875-4
eBook Packages: Springer Book Archive