Intravenous Potassium Infusion Reverses Skeletal Muscle Fatigue

  • R. Kiiski
  • E. Fernandez
  • G. Gutierrez
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 361)

Abstract

Intracellular potassium loss has been implicated as the basis of skeletal muscle fatigue (1). A decrease in the cell membrane K+ gradient diminishes the action potential. In turn, Ca++ release decreases and a smaller tension is developed. The largest K+ losses have been reported during high-intensity, dynamic exercise. The purpose of this study was to determine the effect of KC1 infusion on hindlimb forces in rabbits.

Keywords

Fatigue Lactate 

Reference

  1. 1.
    Sjogaard G. Exercise-induced muscle fatigue: The significance of potassium. Acta Physiol Scand 1990;suppl 593:1–63Google Scholar

Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • R. Kiiski
    • 1
  • E. Fernandez
    • 1
  • G. Gutierrez
    • 1
  1. 1.Division of Pulmonary and Critical Care MedicineUniversity of Texas Health Science CenterHoustonUSA

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