Intravenous Potassium Infusion Reverses Skeletal Muscle Fatigue
Intracellular potassium loss has been implicated as the basis of skeletal muscle fatigue (1). A decrease in the cell membrane K+ gradient diminishes the action potential. In turn, Ca++ release decreases and a smaller tension is developed. The largest K+ losses have been reported during high-intensity, dynamic exercise. The purpose of this study was to determine the effect of KC1 infusion on hindlimb forces in rabbits.
KeywordsMuscle Fatigue Skeletal Muscle Cell Zealand White Rabbit Femoral Nerve Dynamic Exercise
- 1.Sjogaard G. Exercise-induced muscle fatigue: The significance of potassium. Acta Physiol Scand 1990;suppl 593:1–63Google Scholar