Abstract
Filamentous fungus Aspergillus niger var. macrosporus produces two types of extracellular acid endoproteinases, proteinases A and B, commercially called proctases A and B, respectively (1,2). Proteinase A is a non-pepsin-type acid proteinase (1–7), whereas proteinase B has properties of pepsin-type aspartic proteinase. Proteinase B has a molecular mass of about 35 kDa and is inhibited by specific inhibitors of aspartic proteinases such as pepstatin, diazoacetyl-DL-norleucine methyl ester in the presence of cupric ions, and 1,2-epoxy-3-(p-nitrophenoxy)propane (4,8).
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Inoue, H. et al. (1995). Aspergillus Niger Var. Macrosporus Proteinase B. cDNA Cloning, Expression, and Activation of the Proenzyme. In: Takahashi, K. (eds) Aspartic Proteinases. Advances in Experimental Medicine and Biology, vol 362. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1871-6_78
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DOI: https://doi.org/10.1007/978-1-4615-1871-6_78
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