Identification of Five Molecular forms of Cathepsin D in Bovine Milk
Bovine milk contains a wide range of enzymes (1), including zymogens for the proteolytic enzymes plasmin and cathepsin D (2,3). Inside the cell procathepsin D is rapidly processed to the mature cathepsin D found in lysosomes (4). Resulting from the limited availability of procathepsin D the activation process leading to cathepsin D has been less clarified than e.g. the activation pathways of pepsinogen.
KeywordsAffinity Chromatography Molecular Form Bovine Milk Breakthrough Fraction Bovine Spleen
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