New Methods for Diagnosis and Epidemiological Studies of Tuberculosis based on PCR and RFLP
Tuberculosis is a major cause of morbidity and mortality in the world today, particularly in developing and tropical countries. More than one billion individuals are infected with Mycobacterium tuberculosis, and more than 3.5 million people die anually. After years of declining case rates, tuberculosis has returned as a major public health problem in the United States and Europe. The epidemiology of tuberculosis is changing dramatically due to socio-economical problems, the HIV pandemic and the emergence of drug-resistant strains. New methods, based on polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP), for the diagnosis and epidemiological studies of tuberculosis are of critical importance for the development of effective control strategies for the disease.
KeywordsRestriction Fragment Length Polymorphism Mycobacterium Tuberculosis Mycobacterium Bovis Mycobacterial Species Effective Control Strategy
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