Potentiation of Intestinal Secretory Responses to Histamine: Pathophysiologic Implications

  • P. K. Rangachari
  • T. Prior
  • R. A. Bell
Part of the Hans Selye Symposia on Neuroendocrinology and Stress book series (HSSN, volume 2)


Discrimination is the essence of existence, whatever the puerile pundits of political correctness may wish to believe. Mercifully for life in general, Nature in her infinite wisdom exhibits a fine discriminant sense for the welfare of the organism. This capacity is evident in the functioning of the intestinal lining which by its selective absorption of nutrients plays such a crucial role in the body’s economy. This lining is subject to a barrage of influences that impinge on it from both luminal and contraluminal aspects and the fine tuning of its transport properties by these factors keeps the organism in balance. Any disturbance can lead to alterations in gut function that are expressed as either constipation or diarrhea. Thus the release of potent endogenous chemicals during the course of inflammation may profoundly alter gut function2.


Colonic Epithelium Ussing Chamber Diamine Oxidase Methemoglobin Level Diamine Oxidase Activity 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • P. K. Rangachari
  • T. Prior
  • R. A. Bell

There are no affiliations available

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