Abstract
A case of cutaneous B-cell lymphoma (CBCL) is described in which a specific translocation, t(8;14)(q24;q32), was found. As far as we are aware, this is the first report of a cytogenetic abnormality in CBCL.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Boehm T and TH Rabbitts, 1989. A chromosomal basis of lymphoid malignancy in man. Eur. J. Biochem., 185: 1–17.
Busschots AM, ML Geerts, C Mecucci, M Stul, JJ Cassiman and H. Van den Berghe, 1993. A translocation (8;14) in a cutaneous large B-cell lymphoma. Am. J. Clin. Pathol., in press.
Busschots AM, C Mecucci, M Stul, E Vandenberghe, JL Michaux, H Noel, JJ Cassiman and H Van den Berghe, 1991. Translocation (14;19)(q32;q13.1) in a young patient who developed a large cell lymphoma after an initial diagnosis of CLL. Leukemia and Lymphoma, 5: 281–286.
Croce CM and PC Nowell, 1985. Molecular basis of human B cell neoplasia. Blood, 65: I–VII.
Dalla-Favera R, M Bregni, J Erikson, D Patterson, RC Gallo and CM Croce, 1982. Human c-myc oncgene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. Proc. Natl. Acad. Sci. USA, 79: 7824–7827.
Delia D, MG Borrello, E Berti, MA Pierotti, D Biassoni, R Gianotti, E Alessi, MG Rizzetti, R Caputo and G Della Porta, 1989. Clonal immunoglobulin gene rearrangements and normal T-cell receptor, bcl-2 and c-myc genes in primary cutaneous B-cell lymphomas. Cancer Res., 49: 4901–4905.
Gerard-Marchant R, I Hamlin, K Lennert, F Rilke, AG Stansfeld and JAM Van Unnik, 1974. Classification of non-Hodgkin’s lymphomas. Lancet, 2: 406–408.
Hayday AC, SD Gillies, H Saito, C Wood, K Wiman, WS Hayward and S Tonegawa, 1984. Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus. Nature, 307: 334–340.
McKeithan TW, JD Rowley, TB Shows and MO Diaz, 1987. Cloning of the chromosome translocation breakpoint junction of the t(14;19) in chronic lymphocytic leukemia. Proc. Natl. Acad Sci U.S.A., 84: 9257–9260.
Mitelman F, 1991. Catalog of Chromosome Aberrations in Cancer, 4th ed. New York, Wiley-Liss, Editor.
Nishikura K, A Ar-Rushdi, J Erikson, R Watt, G Rovera and CM Croce, 1983. Differential expression of the normal and of the translocated human c-myc oncogenes in B cells. Proc. Natl. Acad. Sci. USA, 80: 4822–4826.
(The) Non-Hodgkin’s lymphoma pathologic classification project, 1982. National Cancer Institute Sponsored Study of Classification of Non-Hodgkin’s lymphomas. Summary and Description of a Working Formulation for Clinical Usage. Cancer (Phila.), 49: 2112–2135.
Sandberg AA, 1990. The Chromosomes in Human Cancer and Leukemia, 2nd ed. New York, Elsevier North-Holland, Inc.
Shiramizu B and I Magrath, 1990. Localization of breakpoints by polymerase chain reactions in Burkitt’s lymphoma with 8;14 translocations. Blood, 75: 1848–1852.
Taub R, I Kirsch, C Morton, G Lenoir, D Swan, S Tronick, S Aaronson and P Leder, 1982. Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proc. Natl. Acad. Sci. USA, 79: 7837–7841.
Tsujimoto Y, LR Finger, J Yunis, PC Nowell and CM Croce, 1984a. Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science, 226: 1097–1099.
Tsujimoto Y, J Yunis, L Onorato-Showe, J Erikson, PC Nowell and CM Croce, 1984b. Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(ll;14) chromosome translocation. Science, 224: 1403–1406.
Vandenberghe E, C De Wolf-Peeters, J Van Den Oord, I Wlodarska, J Delabie, M Stul, J Thomas, JL Michaux, C Mecucci, JJ Cassiman and H Van den Berghe, 1991. Translocation (11;14): A cytogenetic anomaly associated with B-cell lymphomas of nonfollicle centre cell lineage. J. Pathol., 163: 13–18.
Yunis JJ, MM Oken, ME Kaplan, KM Ensrud, RR Howe and A Theologides, 1982. Distinctive chromosomal abnormalities in histologic subtypes of non-Hodgkin’s lymphoma. New Engl. J. Med., 307: 1231–1236.
Yunis JJ, 1983. The chromosomal basis of human neoplasia. Science, 221: 227–236.
Zech L, U Haglund, K Nilsson and G Klein, 1976. Characteristic chromosomal abnormalities in biopsies and lymphoid cell lines from patients with Burkitt and non-Burkitt lymphomas. Int. J. Cancer, 17: 47–56.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1994 Springer Science+Business Media New York
About this chapter
Cite this chapter
Busschots, A.M., Geerts, ML., Mecucci, C., Stul, M., Cassiman, JJ., Van den Berghe, H. (1994). Chromosome Abnormalities in Cutaneous B-Cell Lymphomas. In: Lambert, W.C., Giannotti, B., van Vloten, W.A. (eds) Basic Mechanisms of Physiologic and Aberrant Lymphoproliferation in the Skin. NATO ASI Series, vol 265. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1861-7_34
Download citation
DOI: https://doi.org/10.1007/978-1-4615-1861-7_34
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-5756-8
Online ISBN: 978-1-4615-1861-7
eBook Packages: Springer Book Archive