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Purification and Characterization of a Novel Neurotoxin-Kappa Bungarotoxin

  • Hu Ben-rong
  • Zhang Ze
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 363)

Abstract

Alpha-neurotoxins such as alpha-bungarotoxin and cobrotoxin are now used frequently to characterize the nicotinic receptors in vertebrate skeletal muscle and in electric tissue of some kinds of electric fish. Although they also bind to a variety of neuronal preparations which contain nicotinic receptors, but in most cases, this binding fails to block the nicotinic transmission in neuro-muscular junction. So the physiological significance of alpha-neurotoxins binding sites in neural tissue remains unclear.

Keywords

High Pressure Liquid Chromatography Nicotinic Receptor Electric Fish Crude Venom Ciliary Ganglion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Hu Ben-rong
    • 1
  • Zhang Ze
    • 1
  1. 1.Sun Yat-sen University of Medical SciencesGuangzhouChina

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