Perspective of Neurochemistry in Neurological Disorders

  • Lily C. Tang
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 363)


Degeneration of basal forebrain cholinergic neurons have been considered as one of the earliest and prominent neuropathological features of diseases of the human brain that give rise to loss of memory and dementia including Parkinson’s and Alzheimer’s diseases, and other neurological disorders. Genetic factors, aluminum or other toxic factors, immunological disturbances, disturb glucose metabolism, deficiency of essential nutrients, and stress are some of the etiology. The pathologenesis of the disorder involves not only the structural changes but also neurochemical disturbances and neuroendocrine dysfunction.


Botulinum Toxin Senile Dementia Large Neutral Amino Acid Basal Forebrain Cholinergic Neuron Aged Monkey 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Lily C. Tang
    • 1
    • 2
  1. 1.Department of Experimental TherapeuticsWalter Reed Army Institute of ResearchUSA
  2. 2.SLCT, Inc.BethesdaUSA

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