Cytoarchitecture and Chemistry of Midbrain Dopaminergic Cell Groups
The ventral midbrain contains three dopaminergic cell groups in the rat which have been designated A8, A9, and A10, on their rostrocaudal position and relations with surrounding structures (Dahlström and Fuxe, 1964). Each of these groups has extensive cortical and subcortical projections. These cell groups are closely homologous with those identified in humans, where the A8 cell group is present in the lateral and caudolateral midbrain, the A9 cell group in the substantia nigra, and the heterogeneous A10 cell group, dorsal and medial to the A9 group (Bogerts, 1981; Saper and Petito, 1982; Halliday and Törk, 1986; Pearson et al., 1990).
KeywordsTyrosine Hydroxylase Substantia Nigra Ventral Tegmental Area Pigment Neuron Dorsal Tier
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