Lipid Peroxidation in Normal Pregnancy and Preeclampsia
Increased levels of lipid peroxidation may contribute to the development of endothelial injury which is a key pathogenetic factor in preeclampsia1. Moreover, lipid peroxides per se inhibit prostacyclin formation without affecting thromboxane synthetic pathways2. In this way they could directly contribute to the generation of the thromboxaneprostacyclin imbalance reported in preeclampsia. Increased blood levels of lipid peroxidation products in preeclampsia have been reported by many authors2–4. Levels of lipid peroxidation were usually determined as malondialdehyde (MDA) content measured by the TBA-test.
KeywordsLipid Peroxidation Uric Acid Serum Uric Acid Normal Pregnancy Lipid Peroxidation Product
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