Interactions between Vitamin E, Free Radicals, and Immunity during the Aging Process

  • Jeffrey B. Blumberg
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 366)


There is a substantial amount of experimental evidence indicating a role for oxygen free radicals in the aging process and the development of several chronic diseases common among the elderly. Comparisons between mammalian species reveal a strong correlation between their life span, metabolic generation of free radicals, and tissue concentration of specific antioxidants including α-tocopherol, carotenoids, uric acid, and superoxide dismutase.1 Experimental, clinical, and epidemiological studies have been largely consistent in demonstrating a reduced risk of atherosclerosis, cancer, and other chronic diseases in groups with the highest status of antioxidant vitamins C, E, and/or ß-carotene.2


Arachidonic Acid Lymphocyte Proliferation Eccentric Exercise Influenza Virus Vaccine Maximum Life Span 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Jeffrey B. Blumberg
    • 1
  1. 1.Antioxidants Research LaboratoryUSDA Human Nutrition Research Center on Aging at Tufts UniversityBostonUSA

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