New Directions for Free Radical Cancer Research and Medical Applications
The study of free radicals in biomedical research has dramatically increased in recent years. There is evidence that free radicals play a role in aging, chronic inflammatory or autoimmune diseases, atherosclerosis, and ischemia/reperfusion injury1. Free radicals may also play an important role in several areas of cancer research including the study of carcinogenesis, mechanisms of radiation and chemotherapy action, and the toxicity of therapies. As our knowledge of free radical mechanisms has grown, we have increased our ability to devise strategies in cancer prevention and in modifying the actions of chemotherapeutic agents and radiation. Concomitant with this increased knowledge base, has been the need for further study of free radicals as they relate to carcinogenesis and therapies based upon free radical damage.
KeywordsSemiquinone Radical Free Radical Mechanism Differential Protection Radioprotective Property Nitroxide Spin Probe
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