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Vaccine Design pp 389–412Cite as

Polymer Microspheres for Vaccine Delivery

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Part of the book series: Pharmaceutical Biotechnology ((PBIO,volume 6))

Abstract

Every year millions of people, particularly children, die of diseases for which a vaccine exists (Walsh, 1988; Warren, 1989). Countless others are left blinded, mentally retarded, or severely crippled. The problem is most significant in developing countries where access to health care is poor. In these countries, it is estimated that more than half of the children who receive primary vaccinations do not complete their required booster immunization schedule (Aguado, 1993; Bloom, 1989). These children are left unprotected, accounting for the enormous number of reported deaths.

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Author notes

  1. Masatoshi Chiba

    Present address: Pharmaceutical Development Laboratory, Mitsubishi Kasei Corporation, Kashima-gun, Ibaraki, 314-02, Japan

Authors and Affiliations

  1. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA

    Justin Hanes, Masatoshi Chiba & Robert Langer

Authors
  1. Justin Hanes
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  2. Masatoshi Chiba
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Editors and Affiliations

  1. Genentech, Inc., South San Francisco, California, USA

    Michael F. Powell

  2. Vaxcel, Inc., Norcross, Georgia, USA

    Mark J. Newman

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Hanes, J., Chiba, M., Langer, R. (1995). Polymer Microspheres for Vaccine Delivery. In: Powell, M.F., Newman, M.J. (eds) Vaccine Design. Pharmaceutical Biotechnology, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1823-5_16

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  • DOI: https://doi.org/10.1007/978-1-4615-1823-5_16

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