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Cell cycle-regulated transcription in mammalian cells

  • Jörk Zwicker
  • Rolf Müller
Part of the Progress in Cell Cycle Research book series (PCCR)

Abstract

The periodic, phase-specific transcription of defined sets of genes is a hallmark of cell cycle progression in all organisms (1–3). In this article, we will summarise our current knowledge and views of the mechanisms governing the cross-coupling of cell cycle control and transcriptional regulation in mammalian cells, with particular emphasis on the transcription factor E2F and the retinoblastoma protein pRb (1–3). Excluded from this review will be the genomic response to mitogenic stimulation, which is part of the mitogen-triggered signal transduction cascades rather than a reflection of cell cycle regulation (4).

Keywords

Cell Cycle Regulation Pocket Protein Cell Cycle Machinery Preinitiation Complex Ts13 Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Jörk Zwicker
    • 1
  • Rolf Müller
    • 1
  1. 1.Institut für Molekular-biologie und Tumorforschung (IMT)Philipps-Universität MarburgMarburgGermany

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