Skip to main content
SpringerLink
Log in

Onset of chromosome segregation at the metaphase to anaphase transition of the cell cycle

  • Chapter
Progress in Cell Cycle Research

Part of the book series: Progress in Cell Cycle Research ((PCCR))

Abstract

Chromosome segregation is one of the most important acts in the life of the cell. Unequal inheritance of chromosomes (aneuploidy) is a cause of a number of disorders, particularly in humans, even though eukaryotic cells can arrest or delay the transition from metaphase to anaphase if an event critical to the completion of metaphase is impaired. In this report, we review recent advances in our knowledge of how the complex process of chromosome segregation is coupled with cell cycle progression, and starts at onset of anaphase with sister chromatids separation of the replicated chromosomes.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Dorée, M. (1990) Curr. Opin. Cell Biol. 2, 269–273.

    Article  PubMed  Google Scholar 

  2. Nurse, P. (1990) Nature 344, 503–508.

    Article  PubMed  CAS  Google Scholar 

  3. Nurse, P. (1985) Trends Genet 1, 50–55.

    Article  Google Scholar 

  4. Hunt, T. (1989) Curr. Opin. Cell Biol. 1, 268–274.

    Article  PubMed  CAS  Google Scholar 

  5. Nugent, J.H., Alfa, C.E., Young, T. and Hyams, J.S. (1991) J. Cell Sci 99, 669–674.

    PubMed  CAS  Google Scholar 

  6. Dorée, M. and Galas, S. (1994) FASEB J. 8, 1114–1121.

    PubMed  Google Scholar 

  7. Hyman, A.A. and Mitchison, T.J. (1991) Nature 351, 206–211.

    Article  PubMed  CAS  Google Scholar 

  8. Karsenti, E. (1991) Semin. Cell Biol. 2, 251–260.

    PubMed  CAS  Google Scholar 

  9. Verde, F., Labbé, J.C., Dorée, M. and Karsenti, E. (1990) Nature 342, 505–511.

    Google Scholar 

  10. Buendia, B., Draetta, G. and Karsenti, E. (1992) J. Cell Biol. 116, 1431–1442.

    Article  PubMed  CAS  Google Scholar 

  11. Kalt, A. and Schliwa, M. (1993) Trends Cell Biol. 3, 118–127.

    Article  PubMed  CAS  Google Scholar 

  12. Golsteyn, R.M., Schultz, S.J., Bartek, J., Ziemiecki, A., Ried, T. and Nigg, E.A. (1994) J. Cell Sci. 107, 1509–1517.

    PubMed  CAS  Google Scholar 

  13. Lorca, T., Abrieu, A., Means, A. and Dorée, M. (1994) Biochim. Biophys. Acta, 1223, 325–332.

    Article  PubMed  CAS  Google Scholar 

  14. Bloom, K. (1993) Cell 73, 621–624.

    Article  PubMed  CAS  Google Scholar 

  15. Mitchison, T.J. (1988) Ann. Rev. Cell Biol. 4, 527–549.

    Article  PubMed  CAS  Google Scholar 

  16. Rieder, C.L. and Palazzo, R.E. (1992) J. Cell Sci. 102, 387–392.

    PubMed  CAS  Google Scholar 

  17. Sluder, G. (1979) J. Cell Biol. 80, 674–691.

    Article  PubMed  CAS  Google Scholar 

  18. Guacci, V., Hogan, E. and Koshland, D. (1994) J. Cell Biol. 125, 517–530.

    Article  PubMed  CAS  Google Scholar 

  19. Levan, A. (1938) Hereditas 24 471–486.

    Article  Google Scholar 

  20. Picard, A., Labbé, J.C., Peaucellier, G., Le Bouffant, F., Le Peuch, C.J., and Dorée, M. (1987) Dev. Growth Differ. 29, 93–103.

    Article  CAS  Google Scholar 

  21. Hara, K., Tydeman, P. and Kirschner, M. (1980) Proc. Natl. Acad. Sci. USA 77, 462–466.

    Article  PubMed  CAS  Google Scholar 

  22. Clute, P; and Masui, Y. (1992) Dev. Growth Differ. 34, 27–36.

    Article  Google Scholar 

  23. Cooke, C.A., Heck, M.S. and Earnshaw, W.C. (1987) J. Cell Biol. 105, 2053–2067.

    Article  PubMed  CAS  Google Scholar 

  24. Kung, A.L., Scherwood, S.W., Schimke, R.T. (1990) Proc. Natl. Acad. Sci. USA 87, 9553–9557.

    Article  PubMed  CAS  Google Scholar 

  25. Holm, C., Stearns, T. and Botstein, D. (1989) Mol. Cell. Biol. 9, 159–168.

    PubMed  CAS  Google Scholar 

  26. Uemura, T., Ohkura, H., Adachi, Y., MOrino, K., Shizaki, K. and Yanagida, M. (1987) Cell 50, 917–925.

    Article  PubMed  CAS  Google Scholar 

  27. Summer, A.T. (1992) J. Cell Sci. 103, 105–115.

    Google Scholar 

  28. Downes, C.S., Clarke, D.J., Mullinger, A.M., Giménez-Abian, J.F., Creighton, A.M. and Johnson, R.T. (1994) Nature 372, 467–470.

    Article  PubMed  CAS  Google Scholar 

  29. Clarke, D.J., Johnson, R.T. and Downes, C.S. (1993) J. Cell Sci. 105, 563–569.

    PubMed  CAS  Google Scholar 

  30. Shamu, C.E. and Murray, A.W. (1992) J. Cell Biol. 117, 921–934.

    Article  PubMed  CAS  Google Scholar 

  31. Lorca, T., Cruzalegui, F.H., Fesquet, D., Cavadore, J.C., Méry, J., Means, A. and Dorée, M. (1993) Nature 366, 270–273.

    Article  PubMed  CAS  Google Scholar 

  32. Earnshaw, W.C. (1991) Curr. Opin Cell Biol. 1, 237–244.

    CAS  Google Scholar 

  33. Funabiki, H., Hagan, I., Uzawa, S. and Yanagida, M. (1993) J. Cell Biol. 121, 961–976.

    Article  PubMed  CAS  Google Scholar 

  34. Ghislain, M., Udwardy, A. and Mann, C. (1993) Nature 366, 358–362.

    Article  PubMed  CAS  Google Scholar 

  35. Gordon, C., Mc Gork, G., Dillon, P., Rosen, C. and Hastie, N.D. (1993) Nature 366, 355–357.

    Article  PubMed  CAS  Google Scholar 

  36. Glotzer, M., Murray, A.W. and Kirschner, M.W. (1991) Nature 349, 132–138.

    Article  PubMed  CAS  Google Scholar 

  37. Holloway, S.L., Glotzer, M., King, R.W. and Murray, A.W. (1993) Cell 73, 1393–1402.

    Article  PubMed  CAS  Google Scholar 

  38. Morin, N., Abrieu, A., Lorca, T., Martin, F. and Dorée, M. (1994) EMBO J. 13, 4343–4352.

    PubMed  CAS  Google Scholar 

  39. Seufert, W., Futcher, B. and Jentsch, S. (1995) Nature 373, 78–81.

    Article  PubMed  CAS  Google Scholar 

  40. Surana, U., Amon, A., Dowzer, C., Mc Grew, J., Byers, B. and Nasmyth, K. (1993) EMBO J. 12, 1969–1978..

    PubMed  CAS  Google Scholar 

  41. Minshull, J., Pines, J., Golsteyn, R., Standart, N., Mackie, S., Colman, A., Blow, J., Ruderman, J., Wu, M; and Hunt, T. (1989) J. Cell Sci 512, 77–97.

    Google Scholar 

  42. Whitfield, W.G.F., Gonzalez, C., Maldonado-Codina, G. and Glover, D.M. (1990) EMBO J. 9, 2563–2572.

    PubMed  CAS  Google Scholar 

  43. Yen, T.J., Compton, D.A., Wise, D., Zinkowski, R.P., Brinkley, B.R. Earnshaw, W.C. and Cleveland, D.W. (1991) EMBO J. 10, 1245–1254.

    PubMed  CAS  Google Scholar 

  44. Felix, M.A., Labbé, J.C., Dorée, M., Hunt, T. and Karsenti, E. (1990) Nature 346, 379–382.

    Article  PubMed  CAS  Google Scholar 

  45. Lorca, T., Labbé, J.C., Devault, A., Fesquet, D., Straufeld, U., Nilsson, J., Nygren, P.A., Whlen, M., Cavadore, J.C. and Dorée, M. (1992) J. Cell Sci. 102, 55–62.

    PubMed  CAS  Google Scholar 

  46. Luca, F.C., Shibuya, E.K., Dohrmann, C.E. and Ruderman, J.V. (1991) EMBO J. 10, 4311–4320.

    PubMed  CAS  Google Scholar 

  47. Mordret, G. (1993) Biology of the Cell 79, 193–207.

    Article  PubMed  CAS  Google Scholar 

  48. Haccard, O., Sarcevic, B., Lewellyn, A., Hartley, R., Roy, L., Izumi, T., Erikson, E. and Maller, J.L. (1993) Science 262, 1262–1265.

    Article  PubMed  CAS  Google Scholar 

  49. Lorca, T., Galas, S., Fesquet, D., Devault, A., Cavadore, J.C. and Dorée, M. (1991) EMBO J. 10, 2087–2093.

    PubMed  CAS  Google Scholar 

  50. Kubiak, J.Z., Weber, M., de Pennart, H., Winston, N.J. and Maro, B. (1993) EMBO J. 12, 3773–3778.

    PubMed  CAS  Google Scholar 

  51. Minshull, J., Sun, H., Tonks, N.K. and Murray, A.W. (1994) Cell 79, 475–486.

    Article  PubMed  CAS  Google Scholar 

  52. Tamemoto, H., Kadowaki, T., Tobe, K., Veki, K., Izymi, T., Chatani, Y., Kohno, M., Kasuga, M., Yazaki, Y. and Akanuma, Y. (1992) J. Biol. Chem. 267, 20293–20297.

    PubMed  CAS  Google Scholar 

  53. Rieder, C.L., Schultz, A., Cole, R. and Sluder, G. (1994) J. Cell Biol. 127, 1301–1310.

    Article  PubMed  CAS  Google Scholar 

  54. Gorbsky, G.J. and Ricketts, W.A. (1993) J. Cell Biol. 122, 1311–1321.

    Article  PubMed  CAS  Google Scholar 

  55. Doonan, J.H. and Morris, N.R. (1989) Cell 57, 987–996.

    Article  PubMed  CAS  Google Scholar 

  56. Axton, J., Dombradi, V., Cohen, P.T.W. and Glover, D.M. (1990) Cell 63, 33–46.

    Article  PubMed  CAS  Google Scholar 

  57. Kimoshita, N. Yamano, H., Le Bouffant-Sladeczek, F., Kurooka, H., Ohkura, H., Stone, E.M., Takeuchi, M., Toda, T., Yoshida, T. and Yanagida, M. (1991) Cold Spring Harbor Symposia on Quantitative Biology LVI, 621–628.

    Article  Google Scholar 

  58. Fernandez, A.., Brautigan, D.L. and Lamb, J.J.C. (1992) J. Cell Biol. 116, 1421–1430.

    Article  PubMed  CAS  Google Scholar 

  59. Yamano, H., Ishii, K. and Yanagida, M. (1994) EMBO J. 13, 5310–5318.

    PubMed  CAS  Google Scholar 

  60. Pines, J. and Hunter, T. (1991) J. Cell Biol. 11, 1–17.

    Article  Google Scholar 

  61. Ookata, K., Hisanaga, S., Okano, T., Tachibana, K. and Kishimoto, T. (1992) EMBO J. 11, 1763–1772.

    PubMed  CAS  Google Scholar 

  62. Bailly, E., Pines, J. Hunter, T. and Bornens, M. (1992) J. Cell Sci. 101, 529–545.

    PubMed  CAS  Google Scholar 

  63. Tomkiel, J., Cooke, C.A., Saitsh, H., Bernat, R.L. and Earnshaw, W.C. (1994) J. Cell Biol. 125, 531–545.

    Article  PubMed  CAS  Google Scholar 

  64. Bernat, R.L., Borisy, G.C., Rothfield, N.F. and Earnshaw, W.C. (1990) J. Cell Biol. 111, 1519–1533.

    Article  PubMed  CAS  Google Scholar 

  65. Runge, K.W., Wellinger, R.J. and Zakian, V.A. (1991) Mol. Cell Biol. 11, 2919–2928.

    PubMed  CAS  Google Scholar 

  66. Francisco, L., Wang, W. and Chan, C.S.M. (1994) Mol Cell Biol. 14, 4731–4740.

    PubMed  CAS  Google Scholar 

  67. Sikorski, R.S., Michaud, W.A., Wooton, J.C., Boguski, M.S., Connelly, C. and Hieter, P. (1991) Cold Spring Harbor Symp. Quant. Biol. 56, 663–673.

    Article  PubMed  CAS  Google Scholar 

  68. O’Donnel, K., Osmani, A.H., Osmani, S.A. and Morris, N.R. (1991) J. Cell Sci. 99, 711–719.

    Google Scholar 

  69. Lamb, J.R., Michaud, W.A., Sikorski, R.S. and Hieter, P.A. (1994) EMBO J. 13, 4321–4328.

    PubMed  CAS  Google Scholar 

  70. Hartwell, L.H. and Weinert, T.A. (1989) Science 246, 629–634.

    Article  PubMed  CAS  Google Scholar 

  71. Murray, A.W. (1992) Nature 359, 599–604.

    Article  PubMed  CAS  Google Scholar 

  72. Hoyt, M.A., Totis, L. and Roberts, B.T. (1991) Cell 66, 507–517.

    Article  PubMed  CAS  Google Scholar 

  73. Li, R. and Murray, A.W. (1991) Cell 66, 519–531.

    Article  PubMed  CAS  Google Scholar 

  74. Roberts, B.T., Farr, K.A. and Hoyt, M.A. (1994) Mol. Cell Biol. 14, 8282–8291.

    PubMed  CAS  Google Scholar 

  75. Frankhauser, C., Marks, J., Reymond, A. and Simanis, V. (1993) EMBO J. 12, 2697–2704.

    Google Scholar 

  76. Minet, M., Nurse, P., Thuriaux, P. and Mitchison, J.M. (1979) J. Bact. 137, 440–446.

    PubMed  CAS  Google Scholar 

  77. Chang, F. and Nurse, P. (1993) Trends Genet. 9, 333–335.

    Article  PubMed  CAS  Google Scholar 

  78. Philp, A.V., Axton, J.M., Saunders, R.D.C. and Glover, D.M. (1993) J. Cell Sci. 106, 87–98.

    PubMed  CAS  Google Scholar 

  79. Hirano, T., Funahashi, S., Vemura, T. and Yanagida, M. (1986) EMBO J. 5, 2973–2979.

    PubMed  CAS  Google Scholar 

  80. Samejima, I. and Yanagida, M. (1994) J. Cell Biol 127, 1655–1670.

    Article  PubMed  CAS  Google Scholar 

  81. Hirano, T., Hiroaka, Y. and Yanagida, M. (1988) J. Cell Biol. 106, 1171–1183.

    Article  PubMed  CAS  Google Scholar 

  82. Von Wettstein, D., Rasmussen, S.W. and Holm, P.B. (1984) Ann. Rev. Genet. 18, 331–413.

    Article  Google Scholar 

  83. Weiner, B.M. and Kleckner, N. (1994) Cell 77, 977–991.

    Article  PubMed  CAS  Google Scholar 

  84. Church, K., Nicklas, R.B. and Lin, H.P. (1986) J. Cell Biol. 103, 2765–2773.

    Article  PubMed  CAS  Google Scholar 

  85. Dube, F. and Dufresne, L. (1990) J. Exp. Zool. 256, 323–332.

    Article  CAS  Google Scholar 

  86. Kobayaishi, H., Minshull, J., Ford, C., Golsteyn, R., Poon, R. and Hunt, T. (1991) J. Cell Biol. 114, 755–765.

    Article  Google Scholar 

  87. Van Loon, A.E. Colas, P., Goedermans, HH.J., Neant, I., Dalbon, P. and Guerrier, P. (1991) EMBO J. 10, 3343–3349.

    PubMed  Google Scholar 

  88. Galas, S., Barakat, H., Dorée, M. and Picard, A. (1993) Mol. Biol. Cell 4, 1295–1306.

    PubMed  CAS  Google Scholar 

  89. Furuno, N., Nshizawa, M., Okazaki, K., Tanuka, H., Iwashita, J., Nakajo, H., Ogawa, Y., Sagata, N. (1994) EMBO J. 13, 2399–2410.

    PubMed  CAS  Google Scholar 

  90. Messinger, S.M. and Albertini, D.F. (1991) J. Cell Sci. 100, 289–310.

    PubMed  Google Scholar 

  91. Masui, Y. and Clarke, H. (1979) Int. Rev. Cytol. 57, 185–282.

    Article  PubMed  CAS  Google Scholar 

  92. Neant, I. and Guerrier, P. (1988) Development 102, 505–516.

    CAS  Google Scholar 

  93. Posada, J. and Cooper, J.A. (1992) Science 255, 212–215.

    Article  PubMed  CAS  Google Scholar 

  94. Posada, J., Sanghera, J., Pelech, S., Aebersold, R. and Cooper, J.A. (1991) Mol Cell Biol. 11, 2517–2528.

    PubMed  CAS  Google Scholar 

  95. Verlhac, M.H., de Pennart, H., Maro, B., Cobb, M.H. and Clarke, H.J. (1993) Dev. Viol. 158, 330–340.

    CAS  Google Scholar 

  96. Peaucellier, G. (1977) Exp. Cell Res., 106, 1–14.

    Article  PubMed  CAS  Google Scholar 

  97. Watanabe, N., Hunt, T., Ikawa, Y. and Sagata, N. (1991) Nature 352, 247–248.

    Article  PubMed  CAS  Google Scholar 

  98. Weber, M., Kubiak, J.Z., Arbinghans, R.B., Pines, J. and Maro B. (1991) Dev. Biol. 148, 393–397.

    Article  PubMed  CAS  Google Scholar 

  99. Penrose, L.S. (1933) J. Genet. 27, 219–224.

    Article  Google Scholar 

  100. Sherman, S.L., Takaesu, N., Freeman, S.B., Grantham, M., Phillips, C., Blackston, R.D., Jacobs, P.A., Cockwell, A.E., Freeman, V., Uchida, I., Mickkelsen, M., Kurnit, D.M., Buraczynska, M., Keats, B.J.B. and Hassold, T.J. (1991) Am. J. Human Genet. 49, 608–620.

    CAS  Google Scholar 

  101. Warren, A.C., Chakravarti, A., Wong, C., Slaugenhaupt, S.A., Halloran, S.L., Watkins, P.C., Metaxoton, C. and Antonarakis, S.E. (1987) Science 237, 652–654.

    Article  PubMed  CAS  Google Scholar 

  102. Zheng, C.J. and Byers, B. (1992) Hum. Genet. 90, 1–6.

    Article  PubMed  CAS  Google Scholar 

  103. Eichenlaub-Ritter, U. and Sobek-Klocke, I. (1993) in Chromosome Segregation and Aneuploidy (Vig, B.K., ed.) NATO ASI Series Vol. 72, pp. 173–182, Springer-Verlag, Berlin.

    Chapter  Google Scholar 

  104. Hook, E.B. (1985) in Aneuploidy-etiology and mechanisms (Dellarco, V.L., Voytek, P.E. and Hollaender, A., eds). Plenum, New York, pp. 7–33.

    Chapter  Google Scholar 

  105. Kasjin D., Cavence, W., and Nordenskjold (1991) Ann. Rev. Genet. 25, 281–314.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Centre de Recherches de Biochimie Macromoléculaire, CNRS UPR 9008 and INSERM U 249, Route de Mende, BP 5051, 33033, Montpellier cedex, France

    Marcel Dorée, Christian Le Peuch & Nathalie Morin

Authors
  1. Marcel Dorée
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Christian Le Peuch
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Nathalie Morin
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Centre National de la Recherche Scientifique, Roscoff, France

    Laurent Meijer  & Silvana Guidet  & 

  2. CFSR Biomedical Science Institute, Austin, Texas, USA

    H. Y. Lim Tung

Rights and permissions

Reprints and permissions

Copyright information

© 1995 Springer Science+Business Media New York

About this chapter

Cite this chapter

Dorée, M., Le Peuch, C., Morin, N. (1995). Onset of chromosome segregation at the metaphase to anaphase transition of the cell cycle. In: Meijer, L., Guidet, S., Tung, H.Y.L. (eds) Progress in Cell Cycle Research. Progress in Cell Cycle Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1809-9_25

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-1809-9_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5731-5

  • Online ISBN: 978-1-4615-1809-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation