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The Biology of the Myofibroblast Relationship to Wound Contraction and Fibrocontractive Diseases

  • Chapter
The Molecular and Cellular Biology of Wound Repair

Abstract

The process of wound repair is of vital importance for animals as well as for plants (Shigo, 1985), since a wound perturbs body homeostasis and may result in infection by microorganisms. A wound may occur without or with tissue loss (Robbins et al, 1984). In both cases, but more clearly in the second case, wound healing consists schematically of acute inflammation followed by formation of granulation tissue, a transitional tissue able to retract the wound space, and finally scar formation.

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  1. Department of Pathology, University of Geneva, 1211, Geneva 4, Switzerland

    Omar Skalli & Giulio Gabbiani

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Skalli, O., Gabbiani, G. (1988). The Biology of the Myofibroblast Relationship to Wound Contraction and Fibrocontractive Diseases. In: Clark, R.A.F., Henson, P.M. (eds) The Molecular and Cellular Biology of Wound Repair. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1795-5_17

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