Prolactin pp 317-339 | Cite as

In Vitro Effects of Prolactin on the Lympho-Hemopoietic System

  • Elizabeth L. Hooghe-Peters
  • Zeynep Dogusan
  • Robert Hooghe
Part of the Endocrine Updates book series (ENDO, volume 12)

Abstract

Functional receptors for prolactin (PRL-R) are expressed on many cell types in various tissues, including leukocytes. The PRL-R belongs to the hemopoietin-cytokine receptor family. PRL itself is also expressed in the lympho-hemopoietic system (LHS) where it induces discrete effects. PRL thus qualifies as a cytokine. Effects on the LHS are modest in rodents and man and, though dispensable, PRL is clearly able to affect leukocyte physiology. The present contribution summarizes mainly recent in vitro studies on the role of PRL in the hemopoietic and in the immune systems.

Keywords

Lymphoma Estrogen Dopamine Osteoporosis Flare 

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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Elizabeth L. Hooghe-Peters
    • 1
    • 2
  • Zeynep Dogusan
    • 1
    • 2
  • Robert Hooghe
    • 1
    • 2
  1. 1.Free University of Brussels (V. U.B.)BrusselsBelgium
  2. 2.Flemish Institute for Technological Research (VITO)MolBelgium

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