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Critical Care Infectious Diseases Textbook pp 447–459Cite as

Falciparum Malaria

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Abstract

Malaria is one of the most common infectious diseases in the world today and Plasmodium falciparum is responsible for most of its mortality. Infection with P. falciparum has a wide variety of potential clinical consequences which depend on the age of the patient, their degree of immunity and the duration of infection. More recently it has been noted that polymorphism in both host and parasite impacts on disease pathogenesis and presentation. While highly active anti-malarial agents are available for the treatment of infection, control through parasite and insect vector prevention measures has become largely ineffective due to mosquito and parasite mutation with subsequent development of resistance. The potentially substantial socio-economic and clinical benefits of effective vaccine development underlines the need for future emphasis to be placed on immunoprophylaxis.

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Authors
  1. Charles Feldman
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  2. Guy A. Richards
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Editor information

Editors and Affiliations

  1. Hospital Universitari Joan XXIII, Tarragona, Spain

    Jordi Rello M.D., Ph.D.

  2. University Rovira & Virgili, Tarragona, Spain

    Jordi Rello M.D., Ph.D.

  3. Corporacio Sanitaria Parc Tauli, Sabadell, Barcelona, Spain

    Jordi Valles M.D., Ph.D.

  4. Washington University School of Medicine, St. Louis, Missouri, USA

    Marin H. Kollef M.D.

  5. Barnes-Jewish Hospital, St. Louis, Missouri, USA

    Marin H. Kollef M.D.

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© 2001 Springer Science+Business Media New York

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Feldman, C., Richards, G.A. (2001). Falciparum Malaria. In: Rello, J., Valles, J., Kollef, M.H. (eds) Critical Care Infectious Diseases Textbook. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1679-8_26

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  • DOI: https://doi.org/10.1007/978-1-4615-1679-8_26

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5674-5

  • Online ISBN: 978-1-4615-1679-8

  • eBook Packages: Springer Book Archive

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