Skip to main content
SpringerLink
Log in
Book cover

Thoracic Oncology pp 95–120Cite as

Surgery for Non-Small Cell Lung Cancer

  • Chapter

Part of the book series: Cancer Treatment and Research ((CTAR,volume 105))

Abstract

Surgery remains the primary curative treatment for patients with early stage non-small cell lung cancer (NSCLC). However, the proper use of surgical resection depends on a careful assessment of the extent of disease and of cardiopulmonary function. This chapter reviews the preoperative evaluation of patients with NSCLC and discusses the role of pulmonary resection in their management.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Nagasaki F, Flehinger BJ, Martini N. Complications of surgery in the treatment of carcinoma of the lung. Chest 82:25–9, 1982.

    Article  PubMed  CAS  Google Scholar 

  2. Deslauriers J, Ginsberg RJ, Dubois P, Beaulieu M, Goldberg M, Piraux M. Current operative morbidity associated with elective surgical resection for lung cancer. Can.J.Surg. 32:335–9, 1989.

    PubMed  CAS  Google Scholar 

  3. Ginsberg RJ, Hill LD, Eagan RT, et al. Modern thirty-day operative mortality for surgical resections in lung cancer. J.Thorac.Cardiovasc.Surg. 86:654–8, 1983.

    PubMed  CAS  Google Scholar 

  4. Ritchie JL, ACC/AHA Task Force on Practice Guidelines. ACC/AHA Guidelines for perioperative cardiovascular evaluation for noncardiac surgery. Circulation. 1996;93:1280–317, 1996.

    Google Scholar 

  5. Teplick R. Preoperative cardiac assessment of the thoracic surgical patient. Chest Surg Clin N Amer 7:655–94, 1997.

    CAS  Google Scholar 

  6. Eagle KA, Coley CM, Newell JB, et al. Combining clinical and thallium data optimizes preoperative assessment of cardiac risk before major vascular surgery. Ann Int Med 110:859–66, 1989.

    PubMed  CAS  Google Scholar 

  7. Zibrak JD, O’Donnell CR, Marton K. Indications for pulmonary function testing. Ann Int Med 112:763–71, 1990.

    PubMed  CAS  Google Scholar 

  8. Nakahara K, Olmo K, Hashimoto J, et al. Prediction of postoperative respiratory failure in patients undergoing lung resection for lung cancer. Ann Thorac Surg 46:549–52, 1988.

    Article  PubMed  CAS  Google Scholar 

  9. Ferguson MK, Reeder LB, Mick R. Optimizing selection of patients for major lung resection. J Thorac Cardiovasc Surg 109:275–83, 1995.

    Article  PubMed  CAS  Google Scholar 

  10. Wang J, Olak J, Ferguson MK. Diffusing capacity predicts operative mortality but not long-term survival after resection for lung cancer. J Thorac Cardiovasc Surg 117:581–7, 1999.

    Article  PubMed  CAS  Google Scholar 

  11. Bolliger CT, Wyser C, Roser H, Solèr M, Perruchoud AP. Lung scanning and exercise testing for the prediction of postoperative performance in lung resection candidates at increased risk for complications. Chest 108:341–8, 1995.

    Article  PubMed  CAS  Google Scholar 

  12. Wernly JA, DeMeester TR, Kirchner PT, Myerowitz PD, Oxford DE, Golomb HM. Clinical value of quantitative ventilation-perfusion lung scans in the surgical management of bronchogenic carcinoma. J Thorac Cardiovasc Surg 80:535–43, 1980.

    PubMed  CAS  Google Scholar 

  13. Bolliger CT, Perruchoud AP. Functional evaluation of the lung resection candidate. Eur Respir J 11:198–212, 1998.

    Article  PubMed  CAS  Google Scholar 

  14. Wyser C, Stulz P, Solèr M, et al. Prospective evaluation of an algorithm for the functional assessment of lung resection candidates. Am J Respir Crit Care Med 159:1450–6, 1999.

    PubMed  CAS  Google Scholar 

  15. Nakahara K, Miyoshi S, Nakagawa K. A method for predicting postoperative lung function and its relation to postoperative complications in patients with lung cancer. 1992 update. Ann Thorac Surg 54:1016–7, 1992.

    PubMed  CAS  Google Scholar 

  16. McKenna Jr. RJ, Fischel RJ, Brenner M, Gelb AF. Combined operations for lung volume reduction surgery and lung cancer. Chest 110:885–8, 1996.

    Article  PubMed  Google Scholar 

  17. Cooper JD, Patterson GA, DeMeester SR, Yusen RD, Lefrak SS. Lobectomy combined with lung volume reduction for high risk lung cancer patients with severe emphysema. Chest 110:495, 1996[Abstract].

    Google Scholar 

  18. Epstein SK, Faling LJ, Daly BDT, Celli BR. Predicting complications after pulmonary resection. Preoperative exercise testing vs. a multifactorial cardiopulmonary risk index. Chest 104:694–700, 1993.

    Article  PubMed  CAS  Google Scholar 

  19. Epstein SK, Faling LJ, Daly BDT, Celli BR. Inability to perform bicycle ergometry predicts increased morbidity and mortality after lung resection. Chest. 107:311–6, 1995.

    Article  PubMed  CAS  Google Scholar 

  20. Melendez JA, Carlon VA. Cardiopulmonary risk index does not predict complications after thoracic surgery. Chest 114:69–75, 1998.

    Article  PubMed  CAS  Google Scholar 

  21. Pierce RJ, Copland JM, Sharpe K, Barter CE. Preoperative risk evaluation for lung cancer resection: Predicted postoperative product as a predictor of surgical mortality. Am J Respir Crit Care Med 150:947–55, 1994.

    PubMed  CAS  Google Scholar 

  22. Melendez JA, Barrera R. Predictive respiratory complication quotient predicts pulmonary complications in thoracic surgical patients. Ann Thorac Surg 66:2204, 1998.

    Article  Google Scholar 

  23. Bisson A, Stern M, Caubarrerre I. Preparation of high-risk patients for major thoracic surgery. Chest Surg Clin N Amer 8:541–55, 1998.

    CAS  Google Scholar 

  24. Reilly JJ. Preoperative evaluation of patients. Chest 112:2065–8S, 1997.

    Google Scholar 

  25. Lacasse Y, Wong E, Guyatt GH, King D, Cook DJ, Goldstein RS. Meta-analysis of respiratory rehabilitation in chronic obstructive pulmonary disease. Lancet. 348:1115–9, 1996.

    Article  PubMed  CAS  Google Scholar 

  26. Nomori H, Kobayashi R, Fuyuno G, Morinaga S, Yashima H. Preoperative respiratory muscle training. Assessment in thoracic surgery patients with special reference to postoperative pulmonary complications. Chest. 104:1782–8, 1994.

    Article  Google Scholar 

  27. Jett J, Feins R, Kvale P, et al. Pretreatment evaluation of non-small cell lung cancer. Am J Respir Crit Care Med 156:320–32, 1997.

    Google Scholar 

  28. Winn RJ, Brown NH, Botnick WZ. A comparison of the NCCN and ASCO lung cancer guidelines. Oncology 13:35–9, 1999.

    PubMed  CAS  Google Scholar 

  29. Quint LE, Tummala S, Brisson LJ, et al. Distribution of distant metastases from newly diagnosed non-small cell lung cancer. Ann Thorac Surg 62:246–50, 1996.

    Article  PubMed  CAS  Google Scholar 

  30. Guyatt GH, Cook DJ, Griffiths LE, et al. Surgeons’ assessment of symptoms suggesting extrathoracic metastases in patients with lung cancer. Ann Thorac Surg 68:309–15, 1999.

    Article  PubMed  CAS  Google Scholar 

  31. Silvestri GA, Littenberg B, Colice GL. The clinical evaluation for detecting metastatic lung cancer. A meta-analysis. Am J Respir Crit Care Med 152:225–30, 1995.

    PubMed  CAS  Google Scholar 

  32. Webb WR, Gatsonis C, Zerhouni EA, et al. CT and MR imaging in staging non-small cell bronchogenic carcinoma: Report of the Radiologic Diagnostic Oncology Group. Radiology 178:705–13, 1991.

    PubMed  CAS  Google Scholar 

  33. Martini N, Heelan R, Westcolt J, et al. Comparative merits of conventional, computed tomographic, and magentic resonance imaging in assessing mediastinal involvement in surgically confirmed carcinoma. J Thorac Cardiovasc Surg 90:639–48, 1985.

    PubMed  CAS  Google Scholar 

  34. Patterson GA, Ginsberg RJ, Poon PY, et al. A prospective evaluation of magnetic resonance imaging, computed tomography, and mediastinoscopy in the preoperative assessment of mediastinal node status in bronchogenic carcinoma. J Thorac Cardiovasc Surg 94:679–84, 1987.

    PubMed  CAS  Google Scholar 

  35. McLoud TC, Bourgouin PM, Greenberg RW, et al. Bronchogenic carcinoma: Analysis of staging in the mediastinum with CT by correlative lymph node mapping and sampling. Radiology 182:319–23, 1992.

    PubMed  CAS  Google Scholar 

  36. Arroliga AC, Matthay RA. The role of bronchoscopy in lung cancer. Clin Chest Med 14:87–98, 1993.

    PubMed  CAS  Google Scholar 

  37. Wang K-P. Transbronchial needle aspiration and percutaneous needle aspiration for staging and diagnosis of lung cancer. Clin Chest Med 16:535–52, 1995.

    PubMed  CAS  Google Scholar 

  38. Ginsberg RJ, Rice TW, Goldberg M, Waters PF, Schmocker BJ. Extended cervical mediastinoscopy. A single staging procedure for bronchogenic carcinoma of the left upper lobe. J Thorac Cardiovasc Surg 94:673–8, 1987.

    PubMed  CAS  Google Scholar 

  39. Lee JD, Ginsberg RI. Lung cancer staging: The value of ipsilateral scalene lymph node biopsy performed at mediastinoscopy. Ann Thorac Surg 62:338–41, 1996.

    Article  Google Scholar 

  40. Mentzer SJ, Swanson SJ, DeCamp MM, Bueno R, Sugarbaker DJ. Mediastinoscopy, thoracoscopy and video-assisted thoracic surgery in the diagnosis and staging of lung cancer. Chest 112:239S–41S, 1997.

    Article  PubMed  CAS  Google Scholar 

  41. Gress FG, Savides TJ, Sandler A, et al. Endoscopic ultrasonography, fine-needle aspiration biopsy guided by endoscopic ultrasonography, and computed tomography in the preoperative staging of non-small cell lung cancer: A comparative study. Ann Int Med 127:604–12, 1997.

    PubMed  CAS  Google Scholar 

  42. White P, Jr., Ettinger DS. Tissue is the issue: Is endoscopic ultrasonography with or without fine-needle aspiration biopsy in the staging of non-small cell lung cancer an advance? Ann Int Med 127:643–5, 1997.

    PubMed  Google Scholar 

  43. Steinert HC, Hauser M, Allemann F, et al. Non-small cell lung cancer: Nodal staging with FDG PET versus CT with correlative lymph node mapping and sampling. Radiology 202:441–6, 1997.

    PubMed  CAS  Google Scholar 

  44. Vansteenkiste JF, Stroobants SG, De Leyn PR, et al. Mediastinal lymph node staging with FDG-PET scan in patients with potentially operable non-small cell lung cancer. A prospective analysis of 50 cases. Chest 112:1480–6, 1997.

    Article  PubMed  CAS  Google Scholar 

  45. Weder W, Schmid RA, Bruchhaus H, Hillinger S, von Schulthess GK, Steinert HC. Detection of extrathoracic metastases by positron emission tomography in lung cancer. Ann Thorac Surg 66:886–93, 1998.

    Article  PubMed  CAS  Google Scholar 

  46. Miyake M, Adachi M, Huang C-L, Higashiyama M, Kodama K, Taki T. A novel molecular staging protocol for non-small cell lung cancer. Oncogene 18:2397404, 1999.

    Google Scholar 

  47. The Lung Cancer Study Group, Ginsberg RJ, Rubinstein LV. Randomized trial of lobectomy versus limited resection for T1 NO non-small cell lung cancer. Ann Thorac Surg 60:615–23, 1995.

    Article  Google Scholar 

  48. Martini N, Burt ME, Bains MS, McCormack PM, Rusch VW, Ginsberg RI. Survival after resection of stage II non-small cell lung cancer. Ann Thorac Surg 54:460–6, 1992.

    Article  PubMed  CAS  Google Scholar 

  49. Izbicki JR, Thetter O, Habekost M, et al. Radical systematic mediastinal lymphadenectomy in non-small cell lung cancer: A randomized controlled trial. Br J Surg 81:229–35, 1994.

    Article  PubMed  CAS  Google Scholar 

  50. Graham ANJ, Chan KJM, Pastorino U, Goldstraw P. Systematic nodal dissection in the intrathoracic staging of patients with non-small cell lung cancer. J Thorac Cardiovasc Surg 117:246–51, 1999.

    Article  PubMed  CAS  Google Scholar 

  51. McCaughan BC, Martini N, Bains MS, McCormack PM. Chest wall invasion in carcinoma of the lung. Therapeutic and prognostic implications. J Thorac Cardiovasc Surg 89:836–41, 1985.

    PubMed  CAS  Google Scholar 

  52. Downey RI, Martini N, Rusch VW, Bains MS, Korst RI, Ginsberg RI. Extent of chest wall invasion and survival in patients with lung cancer. Ann Thorac Surg 68:188–93, 1999.

    Article  PubMed  CAS  Google Scholar 

  53. Pitz CCM, de la Rivière AB, Elbers HRJ, Westermann CJJ, van den Bosch JMM. Surgical treatment of 125 patients with non-small cell lung cancer and chest wall involvement. Thorax 51:846–50, 1996.

    Article  PubMed  CAS  Google Scholar 

  54. Albertucci M, DeMeester TR, Rothberg M, Hagen JA, Santoscoy R, Smyrk TC. Surgery and the management of peripheral lung tumors adherent to the parietal pleura. J Thorac Cardiovasc Surg 103:8–13, 1992.

    PubMed  CAS  Google Scholar 

  55. Pairolero PC, Arnold PG. Chest wall tumors. Experience with 100 consecutive patients. J Thorac Cardiovasc Surg 90:367–72, 1985.

    PubMed  CAS  Google Scholar 

  56. Deschamps C, Tirnaksiz BM, Darbandi R, et al. Early and long-term results of prosthetic chest wall reconstruction. J Thorac Cardiovasc Surg 177:588–92, 1999.

    Article  Google Scholar 

  57. McCormack P, Bains MS, Beattie EJ, Jr., Martini N. New trends in skeletal reconstruction after resection of chest wall tumors. Ann Thorac Surg 31:45–52, 1981.

    Article  PubMed  CAS  Google Scholar 

  58. Spaggiari L, Rusca M, Carbognani P, Solli P. Hemivertebrectomy for apical chest tumors: Is risk justified by the outcome? Ann Thorac Surg 65:1515–7, 1998.

    Article  PubMed  CAS  Google Scholar 

  59. Pancoast HK. Henry K. Pancoast describes suprior pulmonary sulcus tumor. Surgical Rounds. January:29–32, 1980.

    Google Scholar 

  60. Shaw RR, Paulson DL, Kee JL, Jr. Treatment of the superior sulcus tumor by irradiation followed by resection. Ann Surg 7:29–40, 1961.

    Article  Google Scholar 

  61. Ginsberg RJ, Martini N, Zaman M, et al. Influence of surgical resection and brachytherapy in the management of superior sulcus tumor. Ann Thorac Surg 57:1440–5, 1994.

    Article  PubMed  CAS  Google Scholar 

  62. Hagan MP, Choi NC, Mathisen DJ, Wain JC, Wright CD, Grillo HC. Superior sulcus lung tumors: Impact of local control on survival. J Thorac Cardiovasc Surg 117:1086–94, 1999.

    Article  PubMed  CAS  Google Scholar 

  63. Rusch VW, Parekh KR, Leon L, et al. Factors determining outcome after surgical resection of T3 and T4 lung cancers of the superior sulcus. J Thorac Cardiovasc Surg “in press”, 2000.

    Google Scholar 

  64. Paulson DL. Extended resection of bronchogenic carcinoma in the superior pulmonary sulcus. Surgical Rounds January:10–21, 1980.

    Google Scholar 

  65. Mathisen DJ, Grillo HC. Carinal resection for bronchogenic carcinoma. J Thorac Cardiovasc Surg 102:16–23, 1991.

    PubMed  CAS  Google Scholar 

  66. Spaggiari L, Pastorino U. Transmanubrial approach with antero-lateral thoracotomy for apical chest tumor. Ann Thorac Surg 68:590–3, 1999.

    Article  PubMed  CAS  Google Scholar 

  67. Bains MS, Ginsberg RJ, Jones WG, et al. The clamshell incision. An improved approach to bilateral pulmonary and mediastinal tumor. Ann Thorac Surg 58:303, 1994.

    Article  Google Scholar 

  68. Martini N, Yellin A, Ginsberg RJ, et al. Management of non-small cell lung cancer with direct mediastinal involvement. Ann Thorac Surg 58:1447–51, 1994.

    Article  PubMed  CAS  Google Scholar 

  69. Nakahashi H, Yasumoto K, Ishida T, et al. Results of surgical treatment of patients with T3 non-small cell lung cancer. Ann Thorac Surg 46:178–81, 1988.

    Article  PubMed  CAS  Google Scholar 

  70. Pitz CCM, de la Rivière AB, Elbers HRJ, Westermann CJJ, van den Bosch JM. Results of resection of T3 non-small cell lung cancer invading the mediastinum or main bronchus. Ann Thorac Surg 62:1016–20, 1996.

    Article  PubMed  CAS  Google Scholar 

  71. Weksler B, Bains M, Burt M, et al. Resection of lung cancer invading the diaphragm. J Thorac Cardiovasc Surg 114:500–1, 1997.

    Article  PubMed  CAS  Google Scholar 

  72. Faber LP, Jensik RJ, Kittle CF. Results of sleeve lobectomy for bronchogenic carcinoma in 101 patients. Ann Thorac Surg 37:279–85, 1984.

    Article  PubMed  CAS  Google Scholar 

  73. Mehran RJ, Deslauriers J, Piraus M, Beaulieu M, Guimont C, Brisson J. Survival related to nodal status after sleeve resection for lung cancer. J Thorac Cardiovasc Surg 107:576–82, 1994.

    PubMed  CAS  Google Scholar 

  74. Suen H-C, Meyers BF, Guthrie T, et al. Favorable results after sleeve lobectomy or bronchoplasty for bronchial malignancies. Ann Thorac Surg 67:1557–62, 1999.

    Article  PubMed  CAS  Google Scholar 

  75. Martini N, Flehinger BJ, Zaman MB, Beattie EJ, Jr. Results of resection in non-oat cell carcinoma of the lung with mediastinal lymph node metastases. Ann Surg 198:386–97, 1983.

    Article  PubMed  CAS  Google Scholar 

  76. Martini N, Flehinger BJ. The role of surgery in N2 lung cancer. Surg Clinics N Amer 67:1037–49, 1987.

    CAS  Google Scholar 

  77. Suzuki K, Nagai K, Yoshida J, Nishimura M, Takahashi K, Nishiwaki Y. The prognosis of surgically resected N2 non-small cell lung cancer: The importance of clinical N status. J Thorac Cardiovasc Surg 118:145–53, 1999.

    Article  CAS  Google Scholar 

  78. Pearson FG, Delarue NC, Ilves R, Todd TRJ, Cooper JD. Significance of positive superior mediastinal nodes identified at mediastinoscopy in patients with resectable cancer of the lung. J Thorac Cardiovasc Surg 83:1–11, 1982.

    PubMed  CAS  Google Scholar 

  79. Okada M, Tsubota N, Yoshimura M, Miyamoto Y, Matsuoka H. Prognosis of completely resected pN2 non-small cell lung carcinomas: What is the significant node that affects survival? J Thorac Cardiovasc Surg 118:270–5, 1999.

    Article  PubMed  CAS  Google Scholar 

  80. Patterson GA, Piazza D, Pearson FG, et al. Significance of metastatic disease in subaortic lymph nodes. Ann Thorac Surg 43:155–9, 1987.

    Article  PubMed  CAS  Google Scholar 

  81. Perez CA, Pajak TF, Rubin P, et al. Long-term observations of the patterns of failure in patients with unresectable non-oat cell carcinoma of the lung treated with definitive radiotherapy. Report by the Radiation Therapy Oncology Group. Cancer. 59:1874–81, 1987.

    Article  PubMed  CAS  Google Scholar 

  82. Keller SM, Adak S, Wagner H, et al. Prospective randomized trial of postoperative adjuvant therapy in patients with completely resected stages II and IIIA non-small cell lung cancer: An intergroup trial (E3590). Proc ASCO. 18:465a, 1999[Abstract].

    Google Scholar 

  83. Deslauriers J, Jacques LF. Sleeve pneumonectomy. Chest Surg Clin N Amer 5:297–313, 1995.

    CAS  Google Scholar 

  84. Mitchell JD, Mathisen DJ, Wright CD, et al. Clinical experience with carinal resection. J Thorac Cardiovasc Surg 117:39–53, 1999.

    Article  PubMed  CAS  Google Scholar 

  85. Klepetko W, Wisser W, Birsan T, et al. T4 lung tumors with infiltration of the thoracic aorta: Is an operation reasonable? Ann Thorac Surg 67:340–4, 1999.

    Article  PubMed  CAS  Google Scholar 

  86. Rendina EA, Venuta F, De Giacomo T, et al. Induction chemotherapy for T4 centrally located non-small cell lung cancer. J Thorac Cardiovasc Surg 117:22533, 1999.

    Article  Google Scholar 

  87. Albain KS, Rusch VW, Crowley JJ, et al. Concurrent cisplatin/etoposide plus chest radiotherapy followed by surgery for stages IIIA (N2) and IIIB non-small cell lung cancer: Mature results of Southwest Oncology Group Phase II study 8805. J Clin Oncol 13:1880–92, 1995.

    PubMed  CAS  Google Scholar 

  88. Albain K, Rusch V, Crowley J, et al. Long-term survival after concurrent cisplatin/etoposide (PE) plus chest radiotherapy (RT) followed by surgery in bulky, stages IIIA (N2) and IIIB non-small cell lung cancer (NSCLC): 6-year outcomes from Southwest Oncology Group study 8805. Proc ASCO 18:467a, 1999 [Abstract].

    Google Scholar 

  89. Eberhardt W, Wilke H, Stamatis G, et al. Preoperative chemotherapy followed by concurrent chemoradiation therapy based on hyperfractionated accelerated radiotherapy and definitive surgery in locally advanced non-small cell lung cancer: Mature results of a Phase II trial. J Clin Oncol 16:622–34, 1998.

    PubMed  CAS  Google Scholar 

  90. Patchell RA, Tibbs PA, Walsh JW, et al. A randomized trial of surgery in the treatment of single metastases to the brain. N Engl J Med 322:494–500, 1990.

    Article  PubMed  CAS  Google Scholar 

  91. Burt M, Wronski M, Arbit E, et al. Resection of brain metastases from non-smallcell lung carcinoma. Results of therapy. J Thorac Cardiovasc Surg 103:399–411, 1992.

    PubMed  CAS  Google Scholar 

  92. Martini N. Surgical treatment of non-small cell lung cancer by stage. Sem Surg Onc 6:248–54, 1990.

    Article  CAS  Google Scholar 

  93. Martini N, Bains MS, Burt ME, et al. Incidence of local recurrence and second primary tumors in resected stage I lung cancer. J Thorac Cardiovasc Surg 109:120–9, 1995.

    Article  PubMed  CAS  Google Scholar 

  94. Thomas P, Rubinstein L, The Lung Cancer Study Group. Cancer recurrence after resection: T 1 NO non-small cell lung cancer. Ann Thorac Surg 49:242–7, 1990.

    Article  PubMed  CAS  Google Scholar 

  95. Johnson BE. Second lung cancers in patients after treatment for an initial lung cancer. J Natl Cancer Inst 90:1335–45, 1998.

    Article  PubMed  CAS  Google Scholar 

  96. Johnson BE, Cortazar P, Chute JP. Second lung cancers in patients successfully treated for lung cancer. Semin Oncol 24:492–9, 1997.

    PubMed  CAS  Google Scholar 

  97. Martini N, Melamed MR. Multiple primary lung cancers. J Thorac Cardiovasc Surg 70:606–12, 1975.

    PubMed  CAS  Google Scholar 

  98. Walsh GL, O’Connor M, Willis KM, et al. Is follow-up of lung cancer patients after resection medically indicated and cost-effective? Ann Thorac Surg 60:1563–72, 1995.

    Article  PubMed  CAS  Google Scholar 

  99. Downey RJ. Follow-up of patients with completely resected lung cancer. Chest 115:1487–8, 1999.

    Article  PubMed  CAS  Google Scholar 

  100. Henschke CI, McCauley DI, Yankelevitz DF, et al. Early lung cancer action project: Overall design and findings from baseline screening. Lancet 354:99–105, 1999.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Memorial Sloan-Kettering Cancer Center, New York, NY, 10021, USA

    Jocelyne Martin MD & Valerie Rusch MD

Authors
  1. Jocelyne Martin MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Valerie Rusch MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. The Johns Hopkins Oncology Center, Bunting Blaustein Cancer Research Building, Baltimore, Maryland, USA

    David S. Ettinger MD

Rights and permissions

Reprints and permissions

Copyright information

© 2001 Springer Science+Business Media New York

About this chapter

Cite this chapter

Martin, J., Rusch, V. (2001). Surgery for Non-Small Cell Lung Cancer. In: Ettinger, D.S. (eds) Thoracic Oncology. Cancer Treatment and Research, vol 105. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1589-0_4

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-1589-0_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5629-5

  • Online ISBN: 978-1-4615-1589-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation