Interactions Between Cardiovascular Pharmacotherapeutics and Potassium Regulation

  • David B. Young
Part of the Basic Science for the Cardiologist book series (BASC, volume 8)


Commonly used medications for hypertension and heart failure affect either glomerular filtration rate or sodium reabsorption in portions of the tubules proximal to the potassium secreting regions, thereby affecting conditions that determine potassium flux from the principal cells to the tubular lumen. As a result, potassium depletion and hypokalemia are common complications associated with treatment of these diseases.


Loop Diuretic Thiazide Diuretic Principal Cell Sodium Reabsorption Distal Nephron 
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Copyright information

© Kluwer Academic Publishers 2001

Authors and Affiliations

  • David B. Young
    • 1
  1. 1.University of Mississippi Medical CenterUSA

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