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Respiratory Instability and Variability: Why is Respiration Such a Mess?

A workshop Summary
  • Michael C K. Khoo
  • G. Benchetrit
  • N. S. Cherniack
  • R. Hughson
  • G. Longobardo
  • D. Paydarfar
  • P. A. Robbins
  • S. Shea
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 499)

Abstract

Although the terms “instability” and “variability” are often used synonymously, the respiratory control system does not have to be unstable for it to produce variable ventilatory patterns. A wide range of physiological mechanisms could lead to respiratory variability, such as fluctuations in state or behavioral inputs, cardiovascular and cerebrovascular influences, time-varying changes in the chemoreflexes, and nonlinear behavior of the central pattern generator. The panel of experts we have assembled here will discuss their latest views on these mechanisms, and comment on how these views have influenced and continue to influence the modeling of the control of breathing.

Keywords

Central Pattern Generator Ventilatory Response Autocorrelative Structure Peripheral Chemoreceptor Respiratory Instability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Michael C K. Khoo
    • 1
  • G. Benchetrit
    • 2
  • N. S. Cherniack
    • 3
  • R. Hughson
    • 4
  • G. Longobardo
    • 5
  • D. Paydarfar
    • 6
  • P. A. Robbins
    • 7
  • S. Shea
    • 8
  1. 1.University of Southern CaliforniaLos AngelesCAUSA
  2. 2.Faculte de Medicine de GrenobleFrance
  3. 3.UMDNJ-New Jersey Medical SchoolNewarkUSA
  4. 4.University of WaterlooCanada
  5. 5.BronxvilleUSA
  6. 6.University of MassachusettsWorcesterUSA
  7. 7.Oxford UniversityUK
  8. 8.Brigham & Women’s HospitalBostonUSA

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